Gerencia de Atención Primaria, Avenida Portugal 47, 05004 Ávila, Spain.
BMC Pregnancy Childbirth. 2011 Mar 8;11:17. doi: 10.1186/1471-2393-11-17.
It is a priority to achieve an adequate nutritional status of iodine during pregnancy since iodine deficiency in this population may have repercussions on the mother during both gestation and post partum as well as on the foetus, the neonate and the child at different ages. According to the WHO, iodine deficiency is the most frequent cause of mental retardation and irrreversible cerebral lesions around the world. However, few studies have been published on the nutritional status of iodine in the pregnant population within the Primary Care setting, a health care level which plays an essential role in the education and control of pregnant women. Therefore, the aim of the present study is: 1.- To know the hygiene-dietetic habits related to the intake of foods rich in iodine and smoking during pregnancy. 2.- To determine the prevalence of iodine deficiency and the factors associated with its appearance during pregnancy.
METHODS/DESIGN: We will perform a cluster randomised, controlled, multicentre trial. Randomisation unit: Primary Care Team.
898 pregnant women over the age of 17 years attending consultation to a midwife during the first trimester of pregnancy in the participating primary care centres.
consumption of iodine-rich foods and iodine deficiency. Points of assessment: each trimester of the gestation.
group education during the first trimester of gestation on healthy hygiene-dietetic habits and the importance of an adequate iodine nutritional status.
descriptive analysis of all variables will be performed as well as multilevel logistic regression. All analyses will be done carried out on an intention to treat basis and will be fitted for potential confounding factors and variables of clinical importance.
Evidence of generalised iodine deficiency during pregnancy could lead to the promotion of interventions of prevention such as how to improve and intensify health care educational programmes for pregnant women.
ClinicalTrials.gov: NCT01301768.
在妊娠期间实现碘的充足营养状态是当务之急，因为该人群中的碘缺乏症可能对孕妇在妊娠和产后期间以及对胎儿、新生儿和不同年龄的儿童产生影响。根据世界卫生组织的说法，碘缺乏症是全世界智力迟钝和不可逆转的脑损伤的最常见原因。然而，在初级保健环境中，关于孕妇的碘营养状况的研究很少发表，初级保健在孕妇的教育和控制方面发挥着重要作用。因此，本研究的目的是：1. 了解与摄入富含碘的食物和吸烟有关的卫生-饮食习惯在怀孕期间。2. 确定碘缺乏症的流行情况及其与怀孕期间出现的相关因素。
方法/设计：我们将进行一项聚类随机对照多中心试验。随机单位：初级保健团队。
898 名年龄在 17 岁以上的孕妇，在参加的初级保健中心向助产士就诊的妊娠早期。
碘丰富食物的摄入和碘缺乏症。评估点：妊娠的每一个 trimester。
在妊娠的第一个 trimester 对孕妇进行团体教育，教育健康的卫生-饮食习惯和充足的碘营养状况的重要性。
将对所有变量进行描述性分析，以及进行多层次逻辑回归。所有分析均将根据意向治疗原则进行，并针对潜在的混杂因素和具有临床意义的变量进行拟合。
如果发现妊娠期间普遍存在碘缺乏症，可能会促使采取预防干预措施，例如如何改善和加强孕妇保健教育计划。
ClinicalTrials.gov：NCT01301768。
