Lange W, Lang R E, Basting C, Unger J W
Department of Anatomy, University of Munich, F.R.G.
Exp Eye Res. 1990 Mar;50(3):313-6. doi: 10.1016/0014-4835(90)90216-h.
The presence of atrial natriuretic peptic/cardiodilatin-immunoreactive material was demonstrated in the lacrimal gland of the domestic pig by high performance liquid chromatography and radioimmunoassay. The immunohistochemical localization revealed a distinct population of cuboid or spindle-shaped ANP/CDD-IR cells in the epithelium of the terminal portion of the secretory tubules. In addition, a moderate number of positive cells was localized intraepithelially in the intralobular ducts as well as the connective tissue between these ducts. Our findings provide a morphological indication that ANP/CDD may play a physiological role in the regulation of sodium transport and secretion in the lacrimal gland.
通过高效液相色谱法和放射免疫分析法，在家猪的泪腺中证实了心房利钠肽/心钠素免疫反应性物质的存在。免疫组织化学定位显示，在分泌小管末端部分的上皮中有一群明显的立方形或梭形心房利钠肽/心钠素免疫反应性（ANP/CDD-IR）细胞。此外，在小叶内导管的上皮内以及这些导管之间的结缔组织中也发现了适量的阳性细胞。我们的研究结果提供了一种形态学依据，表明心房利钠肽/心钠素可能在泪腺钠转运和分泌的调节中发挥生理作用。
