Division of Periodontics, School of Dentistry, EBMSP, Bahia, Brazil.
J Breath Res. 2008 Mar;2(1):017005. doi: 10.1088/1752-7155/2/1/017005. Epub 2008 Mar 7.
This aim of this study was to evaluate the relationship between the formation of volatile sulfur compounds (VSC) and the severity of different kinds of periodontal disease. Twenty patients suffering from biofilm-related periodontal diseases and a control group of ten healthy individuals were selected. The patients were divided according to their periodontal diagnoses: marginal gingivitis (MG/n = 10) and chronic periodontitis (CP/n = 10). The patients received non-surgical therapy that consisted of motivation, scaling and root planing. Two experimental periods were used: T1 = baseline and T2 = final evaluation after three months. The data analysis showed that CP group had a significant reduction (p < 0.05) in probing depth (PD) and clinical attachment level (CAL), and group MG presented a reduction in GI (p < 0.05). There was a significant reduction (p < 0.05) in the aspartate aminotransferase (AST), N-a-benzoyl-DL-arginine-p-nitroanilide (BAPNA) and VSC levels in both MG and CP groups, although the deeper residual pockets led to higher AST and VSC levels in the CP group. Within the limits of the present pilot study, it can be concluded that the non-surgical therapy may influence VSC formation in a manner dependent on periodontal disease severity.
本研究旨在评估挥发性硫化合物（VSC）的形成与不同类型牙周病严重程度之间的关系。选择了 20 名患有生物膜相关牙周病的患者和 10 名健康对照者。根据牙周病诊断将患者分为边缘性龈炎（MG/n=10）和慢性牙周炎（CP/n=10）。患者接受了非手术治疗，包括动机、洁治和根面平整。使用了两个实验期：T1=基线和 T2=三个月后的最终评估。数据分析显示，CP 组的探诊深度（PD）和临床附着丧失（CAL）显著降低（p<0.05），MG 组的牙龈指数（GI）降低（p<0.05）。MG 和 CP 组的天门冬氨酸氨基转移酶（AST）、N-a-苯甲酰-DL-精氨酸-对硝基苯胺（BAPNA）和 VSC 水平均显著降低（p<0.05），尽管 CP 组中较深的残留袋导致 AST 和 VSC 水平升高。在本初步研究的限制范围内，可以得出结论，非手术治疗可能会影响 VSC 的形成，其方式取决于牙周病的严重程度。
