Andoh Hirotaka, Kawaguchi Yoshiharu, Seki Shoji, Asanuma Yumiko, Fukuoka Jun, Ishizawa Shin, Kimura Tomoatsu
Department of Orthopaedic Surgery, University of Toyama Faculty of Medicine, Toyama, Japan.
Asian Spine J. 2011 Mar;5(1):68-72. doi: 10.4184/asj.2011.5.1.68. Epub 2011 Mar 2.
Ependymomas are uncommon tumors that arise in the brain, spinal cord or cauda equina. Myxopapillary ependymomas is located exclusively in the conus medullaris or cauda equina, or film terminale region. In most myxopapillary ependymomas, the histological examination reveals low mitotic activity that is associated with a low MIB-1 labeling index (LI). The prognosis is generally favorable, when the appropriate treatment, including a total resection, is performed. The authors encountered a 39-year-old man with multifocal type of myxopapillary ependymomas compressing the cauda equina from the L2 to L3 level and L5-S1 level. A subtotal resection of the tumor was carried out. The histological examination revealed extremely high mitotic activity with a MIB-1 LI of 9.1%. Therefore, cranio-spinal radiation was added after surgery. The postoperative course was uneventful over the 3.5 year follow-up period.
室管膜瘤是一种罕见的肿瘤，发生于脑、脊髓或马尾。黏液乳头型室管膜瘤仅位于脊髓圆锥、马尾或终丝区域。在大多数黏液乳头型室管膜瘤中，组织学检查显示有丝分裂活性低，且MIB-1标记指数（LI）也低。当进行包括全切除在内的适当治疗时，预后通常良好。作者遇到一名39岁男性，患有多灶性黏液乳头型室管膜瘤，在L2至L3水平和L5-S1水平压迫马尾。对肿瘤进行了次全切除。组织学检查显示有丝分裂活性极高，MIB-1 LI为9.1%。因此，术后加行了全脑全脊髓放疗。在3.5年的随访期内，术后病程平稳。
