Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.
J Endourol. 2011 May;25(5):751-4. doi: 10.1089/end.2010.0400. Epub 2011 Mar 9.
Large stone burden can be treated ureteroscopically, but the treatment often requires more than one procedure. Placement of a preoperative stent may theoretically enhance stone clearance by dilating the ureter to facilitate both access and stone removal. This study determines the impact of stent placement before ureteroscopy on operative time, radiologic stone clearance, and reoperative rates.
We retrospectively reviewed the records of patients who underwent ureteroscopic stone intervention at our institution from 2002 to 2008 by a single surgeon. Nonstented matched controls were used for comparison. Demographics, stone characteristics (size, number, density, and location), presence of preprocedural ureteral stent, operative time, and results of postoperative imaging were compared between the two cohorts. Statistical analysis was performed.
There were 104 patients included in the study (45 prestented and 59 nonstented). Median stone size was 1 cm (range 0.3-4 cm). Overall stone clearance was 95.8%. The median number of procedures was one. Prestenting significantly reduced operative time during first ureteroscopy in patients with large stone requiring multiple ureteroscopies (p = 0.008) and total operative time to stone clearance in patients with stone >1 cm (p = 0.01), but not in patients with stone burdens <1 cm (p = 0.48). Prestenting also significantly reduced reoperative rates in patients with stone burden >1 cm (p = 0.001), especially for stones located in proximal ureter and kidney. Prestenting improves postoperative radiologic clearance, but this was not statistically significant (p = 0.56).
Results show that ureteroscopic lithotripsy of large stone burden can be performed with a high success rate. Preureteroscopic stent placement was associated with a decreased operative time and reoperative rates in patients with larger stone burdens of >1 cm.
大结石负荷可以通过输尿管镜进行治疗,但治疗通常需要多次手术。术前支架置入理论上可以通过扩张输尿管来提高结石清除率,从而方便进入和结石清除。本研究旨在确定输尿管镜检查前支架置入对手术时间、放射学结石清除率和再手术率的影响。
我们回顾性分析了 2002 年至 2008 年间由同一位外科医生在我院行输尿管镜结石介入治疗的患者记录。使用非支架匹配对照进行比较。比较两组患者的人口统计学资料、结石特征(大小、数量、密度和位置)、术前输尿管支架的存在、手术时间和术后影像学结果。进行统计学分析。
本研究共纳入 104 例患者(45 例预置支架,59 例未预置支架)。中位结石大小为 1cm(范围 0.3-4cm)。总体结石清除率为 95.8%。中位手术次数为 1 次。在需要多次输尿管镜检查的大结石患者(p=0.008)和结石>1cm 的患者(p=0.01)中,预置支架可显著缩短首次输尿管镜检查的手术时间,但在结石<1cm 的患者中(p=0.48)无显著差异。在结石>1cm 的患者中,预置支架还显著降低了再手术率(p=0.001),尤其是在近端输尿管和肾脏结石患者中。预置支架可提高术后放射学结石清除率,但无统计学意义(p=0.56)。
结果表明,对于大结石负荷,输尿管镜碎石术可以获得较高的成功率。在结石>1cm 的患者中,术前支架置入与手术时间缩短和再手术率降低有关。