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来自白薯（Ipomoea batatas L.）的一种阿拉伯半乳聚糖蛋白对自发性糖尿病小鼠血糖的影响。

The effects of an arabinogalactan-protein from the white-skinned sweet potato (Ipomoea batatas L.) on blood glucose in spontaneous diabetic mice.

作者信息

Oki Naoko, Nonaka Seiko, Ozaki Sei

机构信息

Research Institute, Fuji-Sangyo Co., Ltd., Marugame, Kagawa, Japan.

出版信息

Biosci Biotechnol Biochem. 2011;75(3):596-8. doi: 10.1271/bbb.100711. Epub 2011 Mar 7.

DOI:10.1271/bbb.100711
PMID:21389600
Abstract

We examined the effects of an arabinogalactanprotein (WSSP-AGP) from Ipomoea batatas L. on hyperglycemia in db/db mice. An oral glucose tolerance test indicated significantly decreased plasma glucose levels by WSSP-AGP. Additionally, an insulin tolerance test found improvement in insulin sensitivity due to treatment with WSSP-AGP. This suggests that amelioration of insulin resistance by WSSP-AGP causes to lead its hypoglycemic effects.

摘要

我们研究了甘薯中的一种阿拉伯半乳聚糖蛋白（WSSP-AGP）对db/db小鼠高血糖的影响。口服葡萄糖耐量试验表明，WSSP-AGP可显著降低血浆葡萄糖水平。此外，胰岛素耐量试验发现，WSSP-AGP治疗可改善胰岛素敏感性。这表明，WSSP-AGP改善胰岛素抵抗导致了其降血糖作用。

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