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哮喘患者的焦虑和抑郁:对哮喘控制的影响。

Anxiety and depression in asthma patients: impact on asthma control.

机构信息

Federal University of São Paulo, Paulista School of Medicine, São Paulo, Brazil.

出版信息

J Bras Pneumol. 2011 Jan-Feb;37(1):13-8. doi: 10.1590/s1806-37132011000100004.

Abstract

OBJECTIVE

There is evidence that asthma is associated with an increase in psychiatric symptoms and mental disorders. This association can make it difficult to achieve asthma control. The purpose of this study was to determine whether the level of asthma control is associated with anxiety and depression.

METHODS

A crosssectional study involving 78 patients with confirmed moderate or severe asthma and under regular treatment at the Asthma Outpatient Clinic of the Federal University of São Paulo Hospital São Paulo, in the city of São Paulo, Brazil. The patients were divided into two groups by asthma control status, as assessed by the asthma control test, and were subsequently compared in terms of demographic, clinical, and spirometric data, as well as scores for asthma quality of life and hospital anxiety/depression.

RESULTS

The sample was predominantly female. Of the 78 patients, 49 (63%) were classified as having uncontrolled asthma. The prevalence of anxiety and of anxiety+depression was significantly higher among patients with uncontrolled asthma than among those with controlled asthma (78% and 100%; p = 0.04 and p = 0.02, respectively), whereas there were no differences between the two groups in terms of the prevalence of depression, spirometry results, or quality of life score.

CONCLUSIONS

In this sample, the prevalence of anxiety symptoms was higher in the patients with uncontrolled asthma than in those with controlled asthma.In the evaluation of asthma patients, the negative impact of mood states ought to be taken into consideration when asthma control strategies are being outlined.

摘要

目的

有证据表明哮喘与精神症状和精神障碍的增加有关。这种关联可能使哮喘控制变得困难。本研究的目的是确定哮喘控制水平是否与焦虑和抑郁有关。

方法

这是一项横断面研究,涉及巴西圣保罗市圣保罗联邦大学附属医院哮喘门诊确诊的 78 例中重度哮喘患者,这些患者正在接受常规治疗。根据哮喘控制测试评估哮喘控制状况,将患者分为两组,然后比较两组的人口统计学、临床和肺功能数据,以及哮喘生活质量和医院焦虑/抑郁评分。

结果

该样本主要为女性。在 78 例患者中,49 例(63%)被归类为未控制的哮喘。与控制组相比,未控制组的焦虑和焦虑+抑郁患病率显著更高(78%和 100%;p=0.04 和 p=0.02),而两组之间的抑郁患病率、肺功能结果或生活质量评分无差异。

结论

在本样本中,未控制组哮喘患者的焦虑症状患病率高于控制组。在评估哮喘患者时,在制定哮喘控制策略时,应当考虑到情绪状态的负面影响。

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