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抑郁和焦虑对哮喘相关生活质量的影响。

Effects of depression and anxiety on asthma-related quality of life.

作者信息

Lomper Katarzyna, Chudiak Anna, Uchmanowicz Izabella, Rosińczuk Joanna, Jankowska-Polanska Beata

出版信息

Pneumonol Alergol Pol. 2016;84(4):212-21. doi: 10.5603/PiAP.2016.0026.

DOI:10.5603/PiAP.2016.0026
PMID:27435347
Abstract

INTRODUCTION

Asthma is the most prevalent chronic disease in adults. It affects their quality of life. Studies confirm that depression and anxiety occurs in asthma patients.

MATERIAL AND METHODS

The study involved 96 patients with asthma divided into two groups: patients with controlled (n = 33) and uncontrolled asthma (n = 63). The analysis of asthma control was performed on the basis of the ACT (Asthma Control Test) results. The study used SF-36 (Short Form 36) questionnaire and HADS (Hospital and Depression Scale) Scale.

RESULTS

An analysis of the correlations between QoL (Quality of Life) and the level of depression revealed a decrease in QoL scores in MCS (Mental Component Score) domain in the group with controlled asthma (71.8 - patients without depression, 53.4 - patients with probable depression, and 51.4 - patients with depression; p = 0.032). A similar analysis of the correlations between QoL and the level of anxiety in this group of patients proved no correlations in PCS (Physical Component Score) and MCS domains. In the group of patients with uncontrolled asthma, anxiety and depression correlated negatively with the QoL in PCS and MCS domains. Anxiety and depression are found in asthma patients, with higher severity observed in patients with uncontrolled asthma. Female gender, the level of asthma control, asthma severity, smoking, as well as diagnoses of anxiety and depression are predictors of a significantly lower QoL in asthma.

CONCLUSIONS

Anxiety and depression are found in asthma patients, with higher severity observed in patients with uncontrolled asthma. Female gender, the level of asthma control, asthma severity, smoking, as well as diagnoses of anxiety and depression are predictors of a significantly lower quality of life in asthma.

摘要

引言

哮喘是成年人中最常见的慢性疾病。它会影响他们的生活质量。研究证实哮喘患者会出现抑郁和焦虑。

材料与方法

该研究纳入了96名哮喘患者,分为两组:病情得到控制的患者(n = 33)和病情未得到控制的哮喘患者(n = 63)。基于哮喘控制测试(ACT)结果对哮喘控制情况进行分析。该研究使用了SF - 36(简明健康状况调查问卷)和医院焦虑抑郁量表(HADS)。

结果

对生活质量(QoL)与抑郁水平之间的相关性分析显示,在病情得到控制的哮喘患者组中,心理成分评分(MCS)领域的生活质量得分降低(无抑郁患者为71.8,可能有抑郁患者为53.4,有抑郁患者为51.4;p = 0.032)。对该组患者生活质量与焦虑水平之间的相关性进行类似分析发现,在生理成分评分(PCS)和心理成分评分领域均无相关性。在病情未得到控制的哮喘患者组中,焦虑和抑郁与PCS和MCS领域的生活质量呈负相关。哮喘患者中存在焦虑和抑郁,在病情未得到控制的哮喘患者中观察到更高的严重程度。女性、哮喘控制水平、哮喘严重程度、吸烟以及焦虑和抑郁的诊断是哮喘患者生活质量显著降低的预测因素。

结论

哮喘患者中存在焦虑和抑郁,在病情未得到控制的哮喘患者中观察到更高的严重程度。女性、哮喘控制水平、哮喘严重程度、吸烟以及焦虑和抑郁的诊断是哮喘患者生活质量显著降低的预测因素。

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