Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Med Oncol. 2012 Jun;29(2):1255-7. doi: 10.1007/s12032-011-9893-0. Epub 2011 Mar 10.
Interstitial pneumonitis after treatment with pegylated liposomal doxorubicin (PLD) has been rarely reported. We describe herein a case of interstitial pneumonitis in a 49-year-old woman with relapsed ovarian carcinoma treated with PLD. Twenty-five days after the second administration of PLD, she presented with fever and dry cough, and chest CT scans revealed bilateral interstitial infiltrates and ground-glass opacities. She was diagnosed to have interstitial pneumonitis induced by PLD. Steroid therapy improved her symptoms.
聚乙二醇脂质体阿霉素（PLD）治疗后发生间质性肺炎的情况很少见。我们在此描述了 1 例复发卵巢癌患者使用 PLD 治疗后发生间质性肺炎的病例。该患者为 49 岁女性，在接受 PLD 第二次治疗后第 25 天出现发热和干咳，胸部 CT 扫描显示双侧间质性浸润和磨玻璃影。诊断为 PLD 引起的间质性肺炎。皮质类固醇治疗改善了她的症状。
