Psychology, Baycrest Centre, Toronto, Ontario, Canada.
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2011 May;18(3):340-52. doi: 10.1080/13825585.2011.553273. Epub 2011 Mar 3.
Building on well-established findings of age-related decline in associative memory, we examined whether the magnitude of age differences depends on the types of associations that are formed. Specifically, because of predominant age-related changes in the hippocampus, we expected to find larger age differences in recognition of between-domain than within-domain associations. Twenty younger and 20 older healthy adults were given two associative recognition tests, using face-name and word-word pairs, that were matched for difficulty level. As hypothesized, a three-way interaction indicated that, relative to item recognition, age differences in associative recognition were greater for between-domain face-name associations than for within-domain word-word associations. This dissociation is consistent with the idea that the hippocampus plays a prominent role in binding information received from distal neocortical regions. The discussion focuses on the roles of recollection and familiarity in supporting associative memory as well as implications for the remediation of age-related memory decline.
基于与年龄相关的联想记忆衰退的既定发现，我们研究了年龄差异的大小是否取决于形成的联想类型。具体来说，由于海马体与年龄相关的变化占主导地位，我们预计在识别跨领域的联想时，会发现比在领域内的联想更大的年龄差异。20 名年轻和 20 名年长的健康成年人接受了两项联想识别测试，使用面孔-名字和单词-单词对，这些测试的难度水平相匹配。正如假设的那样，三向交互表明，与项目识别相比，跨领域面孔-名字联想的联想识别中的年龄差异大于领域内单词-单词联想的年龄差异。这种分离与海马体在将来自远端新皮层区域的信息绑定在一起方面起着重要作用的观点一致。讨论集中在回忆和熟悉在支持联想记忆方面的作用，以及对年龄相关性记忆衰退的矫正的影响。
