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严重的早期下呼吸道感染与加拿大努纳武特地区因纽特学龄前儿童随后的呼吸道疾病相关。

Severe early lower respiratory tract infection is associated with subsequent respiratory morbidity in preschool Inuit children in Nunavut, Canada.

作者信息

Kovesi Thomas Andrew, Cao Zhirong, Osborne Geraldine, Egeland Grace M

机构信息

Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada.

出版信息

J Asthma. 2011 Apr;48(3):241-7. doi: 10.3109/02770903.2011.560320.

DOI:10.3109/02770903.2011.560320
PMID:21391880
Abstract

BACKGROUND

Inuit children in Nunavut, Canada, have high rates of lower respiratory tract infection (LRTI) early in life. Whether this commonly results in chronic respiratory symptoms later in life is unknown.

METHODS

A cross-sectional survey of 3- to 5-years-old Inuit children was conducted in all three regions of Nunavut, as part of the "Qanuippitali, what about us, how are we?" survey.

RESULTS

Reported chronic cough and wheezing were common in preschool Inuit children, although reported asthma diagnosed by a healthcare professional was uncommon. The presence of smokers in the home tended to be associated with severe LRTI in the first 2 years of life. Reported wheezing as well as reported bronchitis or pneumonia in the previous 12 months was significantly associated with severe LRTI in the first 2 years of life. Reported wheezing was also strongly associated with reported bronchitis or pneumonia in the past 12 months. The prevalence of chronic moist cough could not be clearly assessed, due to limitations in the questionnaire.

INTERPRETATION

Severe LRTI in the first 2 years of life was associated with ongoing respiratory morbidity in preschool Inuit children, although symptoms appeared to lessen in severity over time.

摘要

背景

加拿大努纳武特地区的因纽特儿童在幼年时下呼吸道感染(LRTI)发生率较高。这种情况是否通常会导致其在日后生活中出现慢性呼吸道症状尚不清楚。

方法

作为“Qanuippitali,我们呢,我们怎么样?”调查的一部分,在努纳武特的所有三个地区对3至5岁的因纽特儿童进行了横断面调查。

结果

尽管经医疗保健专业人员诊断的哮喘并不常见,但慢性咳嗽和喘息在因纽特学龄前儿童中很常见。家中有吸烟者往往与儿童出生后头两年的严重下呼吸道感染有关。在过去12个月中报告的喘息以及支气管炎或肺炎与出生后头两年的严重下呼吸道感染显著相关。报告的喘息也与过去12个月中报告的支气管炎或肺炎密切相关。由于问卷存在局限性,慢性湿性咳嗽的患病率无法得到明确评估。

解读

因纽特学龄前儿童出生后头两年的严重下呼吸道感染与持续的呼吸道疾病相关,尽管症状似乎会随着时间推移而减轻。

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