恶性疟原虫多药耐药基因型，缅甸。
Multidrug-resistant genotypes of Plasmodium falciparum, Myanmar.
机构信息
Kunming Medical University, Yunnan, People's Republic of China.
出版信息
Emerg Infect Dis. 2011 Mar;17(3):498-501. doi: 10.3201/eid1703.100870.
Abstract
We performed a molecular epidemiologic survey of mutations associated with drug-resistance genes in Plasmodium falciparum in northeastern Myanmar. In this region, 3 highly mutated drug-resistance haplotypes and 1 associated with decreased quinine susceptibility were prevalent, which suggests that parasites may be resistant to multiple commonly used antimalarial drugs.
摘要
我们对缅甸东北部与耐药基因相关的疟原虫突变进行了分子流行病学调查。在该地区，有 3 种高度突变的耐药单倍型和 1 种与降低奎宁敏感性相关的单倍型流行，这表明寄生虫可能对多种常用抗疟药物具有耐药性。
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