McKenzie Harold C
Marion duPont Scott Equine Medical Center, Virginia/Maryland Regional College of Veterinary Medicine, Virginia Polytechnic and State University, 17690 Old Waterford Road, Leesburg, VA 20176, USA.
Vet Clin North Am Equine Pract. 2011 Apr;27(1):59-72. doi: 10.1016/j.cveq.2010.12.008.
Hyperlipidemia is the presence of elevated lipid concentrations in the blood and is associated with periods of negative energy balance and physiologic stress. In increased concentrations, circulating lipids typically occur in the triglyceride form, which may interfere with numerous normal physiologic functions, particularly by reducing insulin sensitivity. Although the hyperlipidemia risk is greatest in ponies, miniature horses, and donkeys, all equids are at risk if they are in a situation involving negative energy balance. The sedentary lifestyle of many modern horses and the frequent feeding of high-carbohydrate diets contribute substantially to the risk of excessive fat mobilization and the development of hyperlipidemias.
高脂血症是指血液中脂质浓度升高,与负能量平衡期和生理应激有关。在浓度升高时,循环脂质通常以甘油三酯形式存在,这可能会干扰许多正常生理功能,特别是通过降低胰岛素敏感性来实现。尽管高脂血症风险在矮种马、迷你马和驴中最高,但如果所有马科动物处于负能量平衡状态,它们都有风险。许多现代马匹的久坐生活方式和高碳水化合物饮食的频繁投喂,极大地增加了脂肪过度动员和高脂血症发生的风险。