School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.
J Pediatr. 2011 Aug;159(2):211-4.e1. doi: 10.1016/j.jpeds.2011.01.037. Epub 2011 Mar 10.
To investigate whether infants with a score <50 on the Bayley Scales of Infant Development, Second Edition (BSID-II) demonstrated differences in functional ability, and to assess whether the Bayley Developmental Quotients (DQs) indicated such differences.
Preterm infants (n = 67; 47 boys) with posthemorrhagic ventricular dilatation were evaluated at 25 months past term age using the BSID-II and grading of functional ability. Mental and Motor Bayley DQs were derived and compared with functional ability.
Among the 34 subjects (51%) with a BSID-II score <50, there were clinically significant differences in the ability to walk, sit, eat, speak, and see. In all subjects, there were significant differences in Mental and Motor Bayley DQs based on grade of disability in each domain except hearing.
Bayley DQ quantified the spread of functional ability in all children, provided a continuous parameter to compare ability in severely delayed children, and should be considered in future therapeutic trials of infants with brain injury.
研究在贝利婴幼儿发展量表第二版（BSID-II）中得分＜50 的婴儿是否在功能能力上存在差异，并评估贝利发育商（DQ）是否能表明这些差异。
对胎龄纠正后 25 个月时患有脑室内出血后扩张的早产儿（n=67；男 47 例）使用 BSID-II 和功能能力分级进行评估。得出精神和运动贝利 DQ，并与功能能力进行比较。
在 BSID-II 得分＜50 的 34 名受试者（51%）中，在行走、坐、吃、说和看的能力方面存在明显的临床差异。在所有受试者中，除听力外，在每个残疾领域的精神和运动贝利 DQ 都与残疾程度存在显著差异。
贝利 DQ 量化了所有儿童的功能能力分布，为比较严重发育迟缓儿童的能力提供了一个连续参数，应在未来的脑损伤婴儿治疗试验中考虑使用。
