Costa R, Cottone C, Cirrincione M, Chinnici M, Scaffidi A
Università degli Studi di Palermo, Istituto di Clinica Medica.
Clin Ter. 1990 Jan 31;132(2):101-4.
The authors studied the action of clebopride on gastric emptying in subjects with non-ulcer dyspepsia by using radioactive isotopes. Eighteen subjects complaining of dyspeptic symptoms were studied in whom the tests undertaken had not shown organic lesions of the digestive tract. Tests with radioactive isotopes were performed before and after administration of clebopride (0.5 mg, three times daily for 15 days). In all patients gastric emptying time was normalized and gastric peristalsis became regular. In addition, in 85% of the patients, symptoms disappeared or were markedly reduced. Side effects requiring withdrawal of the drug were not observed. The above study, therefore, showed clebopride to be a useful drug for the treatment of non-ulcer dyspepsia, thus confirming data found in the literature.
作者通过使用放射性同位素研究了氯波必利对非溃疡性消化不良患者胃排空的作用。对18名主诉消化不良症状且所做检查未显示消化道器质性病变的患者进行了研究。在服用氯波必利（0.5毫克，每日三次，共15天）前后进行了放射性同位素检测。所有患者的胃排空时间恢复正常，胃蠕动变得规律。此外，85%的患者症状消失或明显减轻。未观察到需要停药的副作用。因此，上述研究表明氯波必利是治疗非溃疡性消化不良的有效药物，从而证实了文献中的数据。
