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氯波必利与安慰剂治疗胃排空延迟继发消化不良的双盲对照研究

A double-blind comparison of clebopride and placebo in dyspepsia secondary to delayed gastric emptying.

作者信息

Bavestrello L, Caimi L, Barbera A

出版信息

Clin Ther. 1985;7(4):468-73.

PMID:3893703
Abstract

Seventy-six patients suffering from dyspeptic symptoms secondary to roentgenologically demonstrated delayed gastric emptying were treated with clebopride (0.5 mg TID) or with placebo during a three-month double-blind trial. Clebopride was more effective (P less than or equal to 0.001) than placebo in reducing or relieving symptoms and roentgenological findings associated with delayed gastric emptying. No interactions of clebopride with concomitant drugs or coexisting disorders were observed, and the incidence of side effects was low. We conclude that clebopride will be beneficial in the management of patients with delayed gastric emptying.

摘要

76例经X线检查证实有胃排空延迟继发消化不良症状的患者,在为期3个月的双盲试验中,接受了氯波必利(0.5毫克,每日3次)或安慰剂治疗。在减轻或缓解与胃排空延迟相关的症状及X线检查结果方面,氯波必利比安慰剂更有效(P≤0.001)。未观察到氯波必利与同时使用的药物或并存疾病之间的相互作用,且副作用发生率较低。我们得出结论,氯波必利对胃排空延迟患者的治疗有益。

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A double-blind comparison of clebopride and placebo in dyspepsia secondary to delayed gastric emptying.氯波必利与安慰剂治疗胃排空延迟继发消化不良的双盲对照研究
Clin Ther. 1985;7(4):468-73.
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