Division of Life Sciences, University of Incheon, Incheon 406-840, Korea.
Molecules. 2011 Mar 10;16(3):2334-47. doi: 10.3390/molecules16032334.
Lentinus lepideus is an edible mushroom currently available in Korea. The acetone, methanol and hot water extracts were prepared and assayed for their antioxidant and antityrosinase inhibitory activities. The hot water extract showed the strongest β-carotene-linoleic acid inhibition compared to the other extracts. At 8 mg/mL, the methanolic extract showed a high reducing power of 1.21. The acetone and methanol extracts were more effective in scavenging DPPH radicals than the hot water extract. The strongest chelating effect was obtained from the methanolic extract. Xanthine oxidase and tyrosinase inhibitory activities of the acetonic, methanol and hot water extracts increased with increasing concentration. Gallic acid, chlorogenic acid, vanillin, naringin, naringenin, formononetin, and biochanin-A were detected in the acetonitrile and hydrochloric acid (5:1) solvent extract. This study suggests that fruiting bodies of L. lepideus can potentially be used as a readily accessible source of natural antioxidants.
裂褶菌是一种可食用的蘑菇，目前在韩国有供应。制备了裂褶菌的丙酮、甲醇和热水提取物，并对其抗氧化和酪氨酸酶抑制活性进行了测定。与其他提取物相比，热水提取物对β-胡萝卜素-亚油酸的抑制作用最强。在 8mg/mL 时，甲醇提取物的还原力高达 1.21。丙酮和甲醇提取物清除 DPPH 自由基的效果比热水提取物更有效。甲醇提取物的螯合效果最强。随着浓度的增加，裂褶菌丙酮、甲醇和热水提取物对黄嘌呤氧化酶和酪氨酸酶的抑制活性也随之增加。在乙腈和盐酸（5:1）溶剂提取物中检测到了没食子酸、绿原酸、香草醛、柚皮苷、橙皮苷、芒柄花素和大豆苷元。本研究表明，裂褶菌子实体可能可作为一种易于获得的天然抗氧化剂来源。
