Sumiyama Kazuki, Utsunomiya Kazunori, Ohya Tomohiko, Aihara Hiroyuki, Ikeda Keiichi, Imazu Hiroo, Tamai Naoto, Nagano Hiroshi, Ishinoda Yasuhiro, Tajiri Hisao
Department of Endoscopy, The Jikei University School of Medicine, Tokyo, Japan.
Minim Invasive Ther Allied Technol. 2012 Mar;21(2):71-7. doi: 10.3109/13645706.2011.557384. Epub 2011 Mar 14.
The greater omentum is the largest depot of visceral fat, and recent studies implicate removal of omental fat as a therapeutic option for metabolic syndrome (MS). This study evaluated the technical feasibility of reducing omental fat by using ultrasound-assisted liposuction (UAL) in porcine models. We removed as much omental adipose tissues as possible with a novel ultrasonic aspirator specifically designed for visceral liposuction that was inserted into the peritoneal cavity via the bilateral hypochondrial trocars. The greater part of the omental surface was emulsified and suctioned within 12.4 ± 9.2 (mean ± SD) min. In the survival study, all animals survived for two weeks without clinically evident complications following UAL. Histological examinations confirmed a substantial reduction in omental fat in pigs subjected to UAL. In conclusion, the pilot animal study conducted here demonstrated the technical feasibility of omental liposuction. UAL thus has potential as a relatively non-invasive liposuction approach to treat MS by selectively reducing the visceral fat content of the greater omentum.
大网膜是内脏脂肪的最大储存库，最近的研究表明，切除网膜脂肪是治疗代谢综合征（MS）的一种治疗选择。本研究评估了在猪模型中使用超声辅助吸脂术（UAL）减少网膜脂肪的技术可行性。我们使用专门为内脏吸脂设计的新型超声吸引器，通过双侧肋下套管插入腹腔，尽可能多地去除网膜脂肪组织。网膜表面的大部分在12.4±9.2（平均值±标准差）分钟内被乳化并吸出。在生存研究中，所有动物在接受UAL后均存活两周，无明显临床并发症。组织学检查证实，接受UAL的猪网膜脂肪大量减少。总之，本项初步动物研究证明了网膜吸脂术的技术可行性。因此，UAL作为一种相对非侵入性的吸脂方法，通过选择性减少大网膜的内脏脂肪含量，具有治疗MS的潜力。
