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一种用于脂肪分解的全方位电磁冲击波发生器的研制。

Development of an Omnidirectional-Capable Electromagnetic Shock Wave Generator for Lipolysis.

机构信息

Department of Aeronautics and Astronautics, National Cheng Kung University, No. 1, University Road, Tainan City 701, Taiwan.

出版信息

J Healthc Eng. 2017;2017:9258512. doi: 10.1155/2017/9258512. Epub 2017 May 24.

DOI:10.1155/2017/9258512
PMID:29065664
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5463193/
Abstract

Traditional methods for adipose tissue removal have progressed from invasive methods such as liposuction to more modern methods of noninvasive lipolysis. This research entails the development and evaluation of an omnidirectional-capable flat-coil electromagnetic shock wave generator (EMSWG) for lipolysis. The developed EMSWG has the advantage of omnidirectional-capable operation. This capability increases the eventual clinical usability by adding three designed supports to the aluminum disk of the EMSWG to allow omnidirectional operation. The focal pressures of the developed EMSWG for different operating voltages were measured, and its corresponding energy intensities were calculated. The developed EMSWG was mounted in a downward orientation for lipolysis and evaluated as proof of concept. In vitro tests on porcine fatty tissues have been carried out. It is found that at a 6 kV operating voltage with 1500 shock wave exposures, a 2 cm thick subcutaneous hypodermis of porcine fatty tissue can be ruptured, resulting in a damaged area of 1.39 mm. At a 6.5 kV operating voltage with 2000 shock wave exposures, the damaged area is increased to about 5.20 mm, which can be enlarged by changing the focal point location, resulting in significant lipolysis for use in clinical applications.

摘要

传统的脂肪组织去除方法已经从抽脂等有创方法发展到更现代的无创脂肪分解方法。本研究涉及开发和评估一种用于脂肪分解的全方位平板线圈电磁冲击波发生器 (EMSWG)。所开发的 EMSWG 具有全方位操作的优势。通过在 EMSWG 的铝盘上增加三个设计的支撑,允许全方位操作,从而增加了最终的临床可用性。测量了不同工作电压下开发的 EMSWG 的焦点压力,并计算了相应的能量强度。开发的 EMSWG 以向下的方向安装用于脂肪分解,并作为概念验证进行评估。已经对猪脂肪组织进行了体外测试。结果发现,在 6kV 的工作电压和 1500 次冲击波暴露下,可以破坏厚度为 2cm 的猪脂肪组织的皮下真皮,导致损伤面积为 1.39mm。在 6.5kV 的工作电压和 2000 次冲击波暴露下,损伤面积增加到约 5.20mm,可以通过改变焦点位置来扩大,从而实现显著的脂肪分解,可用于临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/26a40c5ee244/JHE2017-9258512.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/366d9a5a80f9/JHE2017-9258512.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/83ed6392d093/JHE2017-9258512.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/35f308720a83/JHE2017-9258512.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/029e6b8552b2/JHE2017-9258512.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/d16e0d3bde71/JHE2017-9258512.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/74fb0d3750ff/JHE2017-9258512.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/0d0ad11a8799/JHE2017-9258512.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/50ecb1009cc1/JHE2017-9258512.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/26a40c5ee244/JHE2017-9258512.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/366d9a5a80f9/JHE2017-9258512.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/83ed6392d093/JHE2017-9258512.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/35f308720a83/JHE2017-9258512.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/029e6b8552b2/JHE2017-9258512.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/d16e0d3bde71/JHE2017-9258512.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/74fb0d3750ff/JHE2017-9258512.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/0d0ad11a8799/JHE2017-9258512.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/50ecb1009cc1/JHE2017-9258512.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e091/5463193/26a40c5ee244/JHE2017-9258512.009.jpg

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本文引用的文献

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Evidence supporting extracorporeal shock wave therapy for acute and chronic soft tissue wounds.支持体外冲击波疗法治疗急慢性软组织创伤的证据。
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Development and performance evaluation of an electromagnetic-type shock wave generator for lipolysis.用于脂肪分解的电磁式冲击波发生器的研制与性能评估
Rev Sci Instrum. 2014 Jan;85(1):015113. doi: 10.1063/1.4861178.
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