Department of Biology, University of Texas at Arlington, 501 S. Nedderman Drive, Arlington, TX, USA.
Trends Ecol Evol. 2011 May;26(5):222-8. doi: 10.1016/j.tree.2011.02.004. Epub 2011 Mar 11.
Gene duplication is mainly recognized by its primary role in the origin of new genes and functions. However, the idea that gene duplication can be a central player in resolving sexual genetic conflicts through its potential to generate sex-biased and sex-specifically expressed genes, has been almost entirely overlooked. We review recent data and theory that support gene duplication as a theoretically predicted and experimentally supported means of resolving intralocus sexual antagonism. We believe that this role is probably the consequence of sexual conflict for housekeeping genes that are required in males and females, and which are expressed in sexually dimorphic tissues (i.e. where sexually antagonistic selection is exerted). We think that these genes cannot evolve tissue-specific expression unless they duplicate.
基因复制主要通过其在新基因和功能起源中的主要作用而被识别。然而，基因复制可以通过产生性别偏向和性别特异性表达的基因，成为解决性遗传冲突的核心因素的观点，几乎完全被忽视了。我们回顾了最近的数据和理论，这些数据和理论支持基因复制作为一种理论预测和实验支持的方法，用于解决基因内性拮抗作用。我们认为，这种作用可能是由于性冲突对雌雄两性都需要的管家基因造成的，这些基因在性别二态组织中表达（即性拮抗选择施加的地方）。我们认为，除非这些基因发生复制，否则它们无法进化出组织特异性表达。
