通过基因复制解决基因内性冲突。
Intralocus sexual conflict resolved through gene duplication.
机构信息
Department of Biology, University of Texas at Arlington, 501 S. Nedderman Drive, Arlington, TX, USA.
出版信息
Trends Ecol Evol. 2011 May;26(5):222-8. doi: 10.1016/j.tree.2011.02.004. Epub 2011 Mar 11.
Abstract
Gene duplication is mainly recognized by its primary role in the origin of new genes and functions. However, the idea that gene duplication can be a central player in resolving sexual genetic conflicts through its potential to generate sex-biased and sex-specifically expressed genes, has been almost entirely overlooked. We review recent data and theory that support gene duplication as a theoretically predicted and experimentally supported means of resolving intralocus sexual antagonism. We believe that this role is probably the consequence of sexual conflict for housekeeping genes that are required in males and females, and which are expressed in sexually dimorphic tissues (i.e. where sexually antagonistic selection is exerted). We think that these genes cannot evolve tissue-specific expression unless they duplicate.
摘要
基因复制主要通过其在新基因和功能起源中的主要作用而被识别。然而，基因复制可以通过产生性别偏向和性别特异性表达的基因，成为解决性遗传冲突的核心因素的观点，几乎完全被忽视了。我们回顾了最近的数据和理论，这些数据和理论支持基因复制作为一种理论预测和实验支持的方法，用于解决基因内性拮抗作用。我们认为，这种作用可能是由于性冲突对雌雄两性都需要的管家基因造成的，这些基因在性别二态组织中表达（即性拮抗选择施加的地方）。我们认为，除非这些基因发生复制，否则它们无法进化出组织特异性表达。
相似文献
1
Intralocus sexual conflict resolved through gene duplication.通过基因复制解决基因内性冲突。
Trends Ecol Evol. 2011 May;26(5):222-8. doi: 10.1016/j.tree.2011.02.004. Epub 2011 Mar 11.
2
Gene duplication might not resolve intralocus sexual conflict.基因复制可能无法解决基因座内的性冲突。
Trends Ecol Evol. 2011 Nov;26(11):556-7; author reply 558-9. doi: 10.1016/j.tree.2011.07.004. Epub 2011 Aug 3.
3
Gene duplication in the evolution of sexual dimorphism.性二型进化中的基因复制。
Evolution. 2012 May;66(5):1556-66. doi: 10.1111/j.1558-5646.2011.01525.x. Epub 2012 Jan 12.
4
Male-limited evolution suggests no extant intralocus sexual conflict over the sexually dimorphic cuticular hydrocarbons of Drosophila melanogaster.雄性受限进化表明，对于黑腹果蝇两性异形的表皮碳氢化合物，目前不存在基因座内的性冲突。
J Genet. 2011 Dec;90(3):443-52. doi: 10.1007/s12041-011-0109-3.
5
Intralocus sexual conflict.基因座内性冲突
Ann N Y Acad Sci. 2009 Jun;1168:52-71. doi: 10.1111/j.1749-6632.2009.04573.x.
6
Intralocus sexual conflict.基因座内性冲突
Trends Ecol Evol. 2009 May;24(5):280-8. doi: 10.1016/j.tree.2008.12.005. Epub 2009 Mar 21.
7
The resolution of sexual antagonism by gene duplication.通过基因复制解决性拮抗。
Genetics. 2011 Mar;187(3):919-37. doi: 10.1534/genetics.110.123729. Epub 2011 Jan 10.
8
Sexually antagonistic selection on genetic variation underlying both male and female same-sex sexual behavior.对男性和女性同性性行为潜在遗传变异的性对抗选择。
BMC Evol Biol. 2016 May 13;16:88. doi: 10.1186/s12862-016-0658-4.
9
Analyses of nuclearly encoded mitochondrial genes suggest gene duplication as a mechanism for resolving intralocus sexually antagonistic conflict in Drosophila.核编码线粒体基因分析表明，基因复制是解决果蝇种内性拮抗冲突的一种机制。
Genome Biol Evol. 2010;2:835-50. doi: 10.1093/gbe/evq069. Epub 2010 Oct 29.
引用本文的文献
1
An Extension of Muller's Sheltering Hypothesis for the Evolution of Sex Chromosome Gene Content.穆勒庇护假说对性染色体基因含量进化的扩展
Mol Biol Evol. 2025 Jul 30;42(8). doi: 10.1093/molbev/msaf177.
2
The adaptive value of recombination in resolving intralocus sexual conflict by gene duplication.通过基因复制解决基因座内性冲突时重组的适应性价值。
Proc Biol Sci. 2025 Jan;292(2039):20242629. doi: 10.1098/rspb.2024.2629. Epub 2025 Jan 22.
3
Sex-Specific Dominance of Gene Expression in Seed Beetles.种子甲虫中基因表达的性别特异性优势
Mol Biol Evol. 2024 Dec 6;41(12). doi: 10.1093/molbev/msae244.
4
Testis- and ovary-expressed polo-like kinase transcripts and gene duplications affect male fertility when expressed in the Drosophila melanogaster germline.在果蝇生殖系中表达时，睾丸和卵巢表达的polo样激酶转录本及基因重复会影响雄性生育力。
G3 (Bethesda). 2025 Jan 8;15(1). doi: 10.1093/g3journal/jkae273.
5
regulation of an odorant binding protein by a proto-Y chromosome affects male courtship in house fly.原嗅蛋白受拟 Y 染色体调控影响家蝇雄蝇求偶行为。
Elife. 2024 Oct 18;13:e90349. doi: 10.7554/eLife.90349.
6
Prevalent Fast Evolution of Genes Involved in Heterochromatin Functions.常染色质功能相关基因的快速进化。
Mol Biol Evol. 2024 Sep 4;41(9). doi: 10.1093/molbev/msae181.
7
On the resolution of sexual conflict over shared traits.关于共享特征的性冲突的解决。
Proc Biol Sci. 2024 Jul;291(2027):20240438. doi: 10.1098/rspb.2024.0438. Epub 2024 Jul 31.
8
The roles of gene duplications in the dynamics of evolutionary conflicts.基因复制在进化冲突动态中的作用。
Proc Biol Sci. 2024 Jun;291(2024):20240555. doi: 10.1098/rspb.2024.0555. Epub 2024 Jun 12.
9
Recurrent Duplication and Diversification of a Vital DNA Repair Gene Family Across Drosophila.果蝇中关键 DNA 修复基因家族的重复复制和多样化。
Mol Biol Evol. 2024 Jun 1;41(6). doi: 10.1093/molbev/msae113.
10
Dominance reversals: the resolution of genetic conflict and maintenance of genetic variation.显性反转：遗传冲突的解决与遗传变异的维持
Proc Biol Sci. 2024 Mar 13;291(2018):20232816. doi: 10.1098/rspb.2023.2816.
本文引用的文献
1
THE ACCUMULATION OF SEXUALLY ANTAGONISTIC GENES AS A SELECTIVE AGENT PROMOTING THE EVOLUTION OF REDUCED RECOMBINATION BETWEEN PRIMITIVE SEX CHROMOSOMES.作为促进原始性染色体间重组减少进化的选择因子的性拮抗基因的积累。
Evolution. 1987 Jul;41(4):911-914. doi: 10.1111/j.1558-5646.1987.tb05864.x.
2
SEX CHROMOSOMES AND THE EVOLUTION OF SEXUAL DIMORPHISM.性染色体与两性异形的进化
Evolution. 1984 Jul;38(4):735-742. doi: 10.1111/j.1558-5646.1984.tb00346.x.
3
Inbreeding reveals stronger net selection on Drosophila melanogaster males: implications for mutation load and the fitness of sexual females.近亲繁殖揭示了对黑腹果蝇雄蝇更强的净选择：对突变负荷和有性雌性适合度的影响。
Heredity (Edinb). 2011 Jun;106(6):994-1002. doi: 10.1038/hdy.2010.148. Epub 2010 Dec 1.
4
Specialization of a Drosophila capping protein essential for the protection of sperm telomeres.果蝇帽蛋白的特化对于保护精子端粒至关重要。
Curr Biol. 2010 Dec 7;20(23):2090-9. doi: 10.1016/j.cub.2010.11.013. Epub 2010 Nov 18.
5
Analyses of nuclearly encoded mitochondrial genes suggest gene duplication as a mechanism for resolving intralocus sexually antagonistic conflict in Drosophila.核编码线粒体基因分析表明，基因复制是解决果蝇种内性拮抗冲突的一种机制。
Genome Biol Evol. 2010;2:835-50. doi: 10.1093/gbe/evq069. Epub 2010 Oct 29.
6
Origins, evolution, and phenotypic impact of new genes.新基因的起源、进化和表型影响。
Genome Res. 2010 Oct;20(10):1313-26. doi: 10.1101/gr.101386.109. Epub 2010 Jul 22.
7
Sex and the single cell. II. There is a time and place for sex.性与单细胞。二、性有其时间和地点。
PLoS Biol. 2010 May 4;8(5):e1000365. doi: 10.1371/journal.pbio.1000365.
8
The sexually antagonistic genes of Drosophila melanogaster.果蝇的性拮抗基因。
PLoS Biol. 2010 Mar 16;8(3):e1000335. doi: 10.1371/journal.pbio.1000335.
9
Nonallelic gene conversion in the genus Drosophila.非等位基因转换在果蝇属中的研究。
Genetics. 2010 May;185(1):95-103. doi: 10.1534/genetics.110.115444. Epub 2010 Mar 9.
10
Ontogenetic complexity of sexual dimorphism and sex-specific selection.个体发生过程中性别二态性和性别特异性选择的复杂性。
Mol Biol Evol. 2010 Jul;27(7):1570-8. doi: 10.1093/molbev/msq042. Epub 2010 Feb 8.
Zotero 插件