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鲍曼不动杆菌 MDR-TJ 的基因组序列。

Genome sequence of Acinetobacter baumannii MDR-TJ.

机构信息

Department of Physics, Tianjin University, Tianjin 300072, China.

出版信息

J Bacteriol. 2011 May;193(9):2365-6. doi: 10.1128/JB.00226-11. Epub 2011 Mar 11.

DOI:10.1128/JB.00226-11
PMID:21398552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3133082/
Abstract

Acinetobacter baumannii is a pathogenic species of bacteria, identified as an aerobic gram-negative bacterium, that is resistant to most antibiotics. In this study, the MDR-TJ strain was isolated at the Second Hospital of Tianjin Medical University, China, and was found to be resistant to penicillin, cephalosporins, aminoglycosides, quinolones, and also imipenem. The genome sequence of Acinetobacter baumannii strain MDR-TJ was determined by using a combination of 454 pyrosequencing and paired-end sequencing performed with the Roche Genome Sequencer FLX system to generate a scaffolded assembly.

摘要

鲍曼不动杆菌是一种致病性细菌，被鉴定为需氧革兰氏阴性菌，对大多数抗生素具有耐药性。本研究在中国天津医科大学第二医院分离出一株多药耐药性鲍曼不动杆菌（MDR-TJ）株，该菌株对青霉素、头孢菌素类、氨基糖苷类、喹诺酮类和亚胺培南均具有耐药性。采用 454 焦磷酸测序和罗氏基因组测序仪 FLX 系统进行的配对末端测序相结合的方法，测定了鲍曼不动杆菌 MDR-TJ 株的基因组序列，生成了一个支架组装。

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本文引用的文献

1
The RAST Server: rapid annotations using subsystems technology.RAST服务器：使用子系统技术进行快速注释。
BMC Genomics. 2008 Feb 8;9:75. doi: 10.1186/1471-2164-9-75.
2
Ori-Finder: a web-based system for finding oriCs in unannotated bacterial genomes.Ori-Finder：一种用于在未注释细菌基因组中查找oriC的基于网络的系统。
BMC Bioinformatics. 2008 Feb 1;9:79. doi: 10.1186/1471-2105-9-79.
3
An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii.医院中日益严重的威胁：多重耐药鲍曼不动杆菌。
Nat Rev Microbiol. 2007 Dec;5(12):939-51. doi: 10.1038/nrmicro1789.
4
Global challenge of multidrug-resistant Acinetobacter baumannii.多重耐药鲍曼不动杆菌的全球挑战
Antimicrob Agents Chemother. 2007 Oct;51(10):3471-84. doi: 10.1128/AAC.01464-06. Epub 2007 Jul 23.
5
RNAmmer: consistent and rapid annotation of ribosomal RNA genes.RNAmmer：核糖体RNA基因的一致性快速注释
Nucleic Acids Res. 2007;35(9):3100-8. doi: 10.1093/nar/gkm160. Epub 2007 Apr 22.
6
Identifying bacterial genes and endosymbiont DNA with Glimmer.使用Glimmer识别细菌基因和内共生体DNA。
Bioinformatics. 2007 Mar 15;23(6):673-9. doi: 10.1093/bioinformatics/btm009. Epub 2007 Jan 19.
7
GC-Profile: a web-based tool for visualizing and analyzing the variation of GC content in genomic sequences.GC-Profile：一个用于可视化和分析基因组序列中GC含量变化的基于网络的工具。
Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W686-91. doi: 10.1093/nar/gkl040.
8
The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAs.用于检测tRNA和snoRNA的tRNAscan-SE、snoscan和snoGPS网络服务器。
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W686-9. doi: 10.1093/nar/gki366.
9
GeneMark: web software for gene finding in prokaryotes, eukaryotes and viruses.基因标记：用于在原核生物、真核生物和病毒中寻找基因的网络软件。
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W451-4. doi: 10.1093/nar/gki487.
10
ZCURVE: a new system for recognizing protein-coding genes in bacterial and archaeal genomes.Z曲线：一种用于识别细菌和古细菌基因组中蛋白质编码基因的新系统。
Nucleic Acids Res. 2003 Mar 15;31(6):1780-9. doi: 10.1093/nar/gkg254.