印度墨吉对虾浓核病毒（PstDNV）的全核酸序列。
Complete nucleic acid sequence of Penaeus stylirostris densovirus (PstDNV) from India.
机构信息
Department of Fishery Microbiology, Karnataka Veterinary, Animal and Fisheries Sciences University, College of Fisheries, Mangalore 575 002, India.
出版信息
Virus Res. 2011 Jun;158(1-2):37-45. doi: 10.1016/j.virusres.2011.03.005. Epub 2011 Mar 23.
Infectious hypodermal and hematopoietic necrosis virus (IHHNV) of shrimp, recently been classified as Penaeus stylirostris densovirus (PstDNV). The complete nucleic acid sequence of PstDNV from India was obtained by cloning and sequencing of different DNA fragment of the virus. The genome organisation of PstDNV revealed that there were three major coding domains: a left ORF (NS1) of 2001 bp, a mid ORF (NS2) of 1092 bp and a right ORF (VP) of 990 bp. The complete genome and amino acid sequences of three proteins viz., NS1, NS2 and VP were compared with the genomes of the virus reported from Hawaii, China and Mexico and with partial sequence available from isolates from different regions. The phylogenetic analysis of shrimp, insect and vertebrate parvovirus sequences showed that the Indian PstDNV isolate is phylogenetically more closely related to one of the three isolates from Taiwan (AY355307), and two isolates (AY362547 and AY102034) from Thailand.
虾传染性皮下及造血组织坏死病毒（IHHNV），最近被归类为凡纳滨对虾浓核病毒（PstDNV）。通过对病毒不同 DNA 片段的克隆和测序，获得了来自印度的 PstDNV 的完整核酸序列。PstDNV 的基因组结构表明，它有三个主要的编码区域：2001 个碱基对的左开放阅读框（NS1）、1092 个碱基对的中开放阅读框（NS2）和 990 个碱基对的右开放阅读框（VP）。对 NS1、NS2 和 VP 这三种蛋白质的完整基因组和氨基酸序列与来自夏威夷、中国和墨西哥的病毒基因组以及来自不同地区分离株的部分序列进行了比较。对虾、昆虫和脊椎动物细小病毒序列的系统发育分析表明，印度的 PstDNV 分离株与来自台湾的三个分离株中的一个（AY355307）以及来自泰国的两个分离株（AY362547 和 AY102034）在系统发育上更为密切相关。
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