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本文引用的文献

1
Current treatments for infantile hemangiomas.
J Drugs Dermatol. 2010 Feb;9(2):176-80.
2
Propranolol therapy for infantile haemangiomas: review of the literature.普萘洛尔治疗婴幼儿血管瘤：文献综述
Int J Pediatr Otorhinolaryngol. 2010 Apr;74(4):338-42. doi: 10.1016/j.ijporl.2010.01.001. Epub 2010 Feb 1.
3
Propranolol treatment for hemangioma of infancy: risks and recommendations.普萘洛尔治疗婴幼儿血管瘤：风险与建议
Pediatr Dermatol. 2009 Sep-Oct;26(5):610-4. doi: 10.1111/j.1525-1470.2009.00975.x.
4
Propranolol for severe infantile hemangiomas: follow-up report.普萘洛尔治疗严重婴幼儿血管瘤：随访报告。
Pediatrics. 2009 Sep;124(3):e423-31. doi: 10.1542/peds.2008-3458. Epub 2009 Aug 10.
5
Growth characteristics of infantile hemangiomas: implications for management.婴儿血管瘤的生长特征：对治疗的启示
Pediatrics. 2008 Aug;122(2):360-7. doi: 10.1542/peds.2007-2767.
6
Propranolol for severe hemangiomas of infancy.普萘洛尔治疗婴儿重症血管瘤。
N Engl J Med. 2008 Jun 12;358(24):2649-51. doi: 10.1056/NEJMc0708819.
7
Infantile hemangiomas: how common are they? A systematic review of the medical literature.婴儿血管瘤：它们有多常见？对医学文献的系统综述。
Pediatr Dermatol. 2008 Mar-Apr;25(2):168-73. doi: 10.1111/j.1525-1470.2008.00626.x.
8
Multicenter prospective study of ulcerated hemangiomas.溃疡性血管瘤的多中心前瞻性研究。
J Pediatr. 2007 Dec;151(6):684-9, 689.e1. doi: 10.1016/j.jpeds.2007.04.055. Epub 2007 Aug 24.
9
Spastic diplegia and other motor disturbances in infants receiving interferon-alpha.接受α-干扰素治疗的婴儿出现痉挛性双瘫及其他运动障碍。
Laryngoscope. 2004 Jul;114(7):1231-6. doi: 10.1097/00005537-200407000-00017.
10
Oral corticosteroid use is effective for cutaneous hemangiomas: an evidence-based evaluation.口服皮质类固醇对皮肤血管瘤有效：一项基于证据的评估。
Arch Dermatol. 2001 Sep;137(9):1208-13. doi: 10.1001/archderm.137.9.1208.

普萘洛尔在治疗血管瘤中的应用。

Use of propranolol in treating hemangiomas.

机构信息

Department of Pediatrics, BC Children's Hospital, Vancouver, BC V6H 3V4, Canada.

出版信息

Can Fam Physician. 2011 Mar;57(3):302-3.

PMID:21402965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3056677/
Abstract

QUESTION

I see many children with infantile hemangiomas and have read about new therapeutic options such as propranolol. Is this medication effective and safe for treating hemangiomas in children?

ANSWER

Most infantile hemangiomas resolve spontaneously without any need for therapy. In many case series, propranolol has been shown to be effective and safe in treating hemangiomas that cause complications. Further studies are required to determine the optimal dose and duration of propranolol treatment for problematic hemangiomas.

摘要

问题

我见过很多患有婴儿血管瘤的儿童，也了解过一些新的治疗选择，比如普萘洛尔。这种药物对治疗儿童血管瘤是否有效且安全？

答案

大多数婴儿血管瘤会自行消退，无需任何治疗。在许多病例系列研究中，普萘洛尔治疗引起并发症的血管瘤已被证明是有效且安全的。还需要进一步的研究来确定普萘洛尔治疗有问题的血管瘤的最佳剂量和疗程。