State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P R China.
Chem Biodivers. 2011 Mar;8(3):414-30. doi: 10.1002/cbdv.201000022.
The plants of genus Dipsacus, with a wide distribution in Europe, Asia, and Africa, have been used as medicinal agents to treat several diseases, including lime disease, fibromyalgia, bone fracture, and abortion, and especially the Alzheimer's disease and cancer. A large number of studies on plants of genus Dipsacus has revealed cytoprotective properties, inhibition of HIV-1 reverse transcriptase, antinociceptive, and antimicrobial effects, etc. This review compiles all chemical constituents isolated, mainly triterpenoids, iridoids, phenolics, and alkaloids, from the genus Dipsacus over the past few decades together with their structural features, biological activities, and structure-activity relationships.
续断属植物广泛分布于欧洲、亚洲和非洲，已被用作药物治疗多种疾病，包括石灰病、纤维肌痛、骨折和流产，特别是阿尔茨海默病和癌症。大量关于续断属植物的研究揭示了其具有细胞保护、抑制 HIV-1 逆转录酶、镇痛和抗菌等作用。本综述汇集了过去几十年中从续断属植物中分离得到的所有化学成分，主要包括三萜类、环烯醚萜类、酚类和生物碱类，并介绍了它们的结构特征、生物活性和构效关系。
