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New WS9326A congeners from Streptomyces sp. 9078 inhibiting Brugia malayi asparaginyl-tRNA synthetase.
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Discovering new classes of Brugia malayi asparaginyl-tRNA synthetase inhibitors and relating specificity to conformational change.
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Expression, localization and alternative function of cytoplasmic asparaginyl-tRNA synthetase in Brugia malayi.
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An immunodominant antigen of Brugia malayi is an asparaginyl-tRNA synthetase.
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A hybrid structural model of the complete Brugia malayi cytoplasmic asparaginyl-tRNA synthetase.
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Immune Response to Asparaginyl-tRNA Synthetase in Balb/c Mice and Human Clinical Samples of Lymphatic Filariasis.
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Broad anti-pathogen potential of DEAD box RNA helicase eIF4A-targeting rocaglates.
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Natural Products from Actinomycetes Associated with Marine Organisms.
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Asparaginyl-tRNA Synthetase, a Novel Component of Hippo Signaling, Binds to Salvador and Enhances Yorkie-Mediated Tumorigenesis.
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Leveraging a large microbial strain collection for natural product discovery.
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sp. nov., a Novel Marine Sponge-Derived Actinobacterium With Antibacterial Potential Against .
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Capacity building in anthelmintic drug discovery.
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Ivermectin resistance and overview of the Consortium for Anthelmintic Resistance SNPs.
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A hybrid structural model of the complete Brugia malayi cytoplasmic asparaginyl-tRNA synthetase.
J Mol Biol. 2011 Jan 28;405(4):1056-69. doi: 10.1016/j.jmb.2010.11.049. Epub 2010 Dec 4.
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Asparaginyl-tRNA synthetase pre-transfer editing assay.
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Elimination of lymphatic filariasis: do we have the drugs to complete the job?
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Identification of the tirandamycin biosynthetic gene cluster from Streptomyces sp. 307-9.
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Isolation and characterization of tirandamycins from a marine-derived Streptomyces sp.
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Filariasis: new drugs and new opportunities for lymphatic filariasis and onchocerciasis.
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