Yarham Gemma, Clements Ann, Oliver Martin, Morris Christopher, Cumberland Tom, Bryan Megan, Jekler Sasa, Johns Kathy, Mulholland John
Department of Clinical Perfusion Science, Essex Cardiothoracic Centre, Nethermayne, Essex, UK.
Perfusion. 2011 Jul;26(4):263-70. doi: 10.1177/0267659111399951. Epub 2011 Mar 15.
Donor blood supplies are diminishing, becoming more costly and these transfusions lead to higher mortality in cardiac patients. The transfusion risks and the literature highlight the need for an alternative similar to cell salvage to be routinely considered. The Xtra is the first cell saver to be launched since 2001 and will undoubtedly initiate evolution towards the 'next generation' of cell savers. It is also the first to be launched in a new era where the demand for electronic perfusion data management (EPDM) has grown.
The user interface (UI) was easy to use. The increased data entry options improved the quality of the recordable data. The integrated data management system (DMS) was comprehensive. Data was easy to manage and enabled central data compilation, which reduces repeated data, the risk of inconsistent data inventory and provides the potential for research and analyses. The haematocrit of the processed blood is a key quality indicator for cell salvage. The comparison of the manufacturer's integrated protocol, Popt, to our team's own protocol showed that Popt delivered a higher haematocrit on its '1st bowl' (59.1% compared to 57.3%) and its 'total process' end product haematocrit was 0.68% higher. The Popt cycle took an average of 330s, whereas our own settings completed in just over 300s.
The Xtra is a device which will lead the evolution of 'next generation' cell saver technology. The user interface and data management system provide export options and the ability to record the level of data required for good EPDM. This is essential to 'future proof' cell salvage technology. The manufacturer's integrated protocol achieved a higher end product haematocrit than our perfusion team's best practice. The design of the Xtra is contemporary, but the DMS equips this cell saver for the new era that faces both Perfusion and Cardiac Surgery.
供血量正在减少,成本越来越高,而且这些输血会导致心脏病患者死亡率上升。输血风险以及相关文献表明,有必要常规考虑采用类似细胞回收的替代方法。Xtra是自2001年以来推出的首款细胞回收设备,无疑将开启向“下一代”细胞回收设备的演进。它也是在电子灌注数据管理(EPDM)需求增长的新时代推出的首款设备。
用户界面易于使用。增加的数据输入选项提高了可记录数据的质量。集成数据管理系统(DMS)功能全面。数据易于管理,支持集中数据汇编,减少了重复数据、数据清单不一致的风险,并为研究和分析提供了可能性。处理后血液的血细胞比容是细胞回收的关键质量指标。将制造商的集成方案Popt与我们团队自己的方案进行比较,结果显示Popt在其“第一碗”的血细胞比容更高(分别为59.1%和57.3%),其“整个过程”最终产品的血细胞比容高出0.68%。Popt周期平均耗时330秒,而我们自己的设置在300多秒内即可完成。
Xtra是一款将引领“下一代”细胞回收技术演进的设备。用户界面和数据管理系统提供了导出选项以及记录良好EPDM所需数据水平的能力。这对于使细胞回收技术“面向未来”至关重要。制造商的集成方案比我们灌注团队的最佳实践实现了更高的最终产品血细胞比容。Xtra的设计具有现代感,但其DMS使这款细胞回收设备能够适应灌注和心脏外科面临的新时代。