R. SHUKLA, MD., Professor, Department of Neurology, K G's Medical College. Lucknow-226003.
Indian J Psychiatry. 2000 Oct;42(4):397-401.
P300 event related potential was recorded in 115 healthy controls with a mean age of35.9±14.81 years and a male : female ratio of 72 : 43. There was significant difference in the P300 latency in < 40 years as compared to ≥ 40 years group (p< 0.001). There was no significant difference between males and females. There was a strong positive correlation between age and P300 latency (p< 0.001). The regression equation for P300 latency was Y=287.9+1.492x with an SEE of 20.2 (where Y is the P300 latency in ms, x is the age in years, SEE is the standard error of estimate). There was a negative correlation between age and P300 amplitude which was significant in ≥ 40 years age group while in > 40 years age group it was not significant.
在 115 名平均年龄为 35.9±14.81 岁的健康对照中记录了 P300 事件相关电位，男女比例为 72:43。<40 岁组与≥40 岁组的 P300 潜伏期有显著差异（p<0.001）。男女之间无显著差异。年龄与 P300 潜伏期呈强正相关（p<0.001）。P300 潜伏期的回归方程为 Y=287.9+1.492x，SEE 为 20.2（其中 Y 为 P300 潜伏期（ms），x 为年龄（岁），SEE 为估计的标准误差）。年龄与 P300 振幅呈负相关，≥40 岁年龄组有显著相关性，而>40 岁年龄组则无显著相关性。
