Assistant Professor of Psychiatry, Universal College of Medical Sciences, Bhairahawa, Nepal.
Indian J Psychiatry. 2004 Apr;46(2):135-9.
Seventy patients of schizophrenia were divided into two groups based on the presence or absence of substance abusing history in them. Two groups were compared on various socio-demographic and clinical variables. Thirty-eight (54.3%) patients could be diagnosed as having comorbid alcohol/substance abuse/dependence. Seventeen (24.3%) of them were poly-substance abusers. Comorbid substance abusers were predominantly represented by positive syndrome while non-abusers by negative syndrome. In contrast to the report by the most western researchers, most patients in the present study with a diagnosis of substance abusing schizophrenia were married. Similar study from a developing country is rare in the existing literature.
70 名精神分裂症患者根据其是否有物质滥用史分为两组。比较了两组在各种社会人口统计学和临床变量上的差异。38 名（54.3%）患者可被诊断为合并酒精/物质滥用/依赖。其中 17 名（24.3%）为多物质滥用者。合并物质滥用者主要表现为阳性综合征，而非滥用者主要表现为阴性综合征。与大多数西方研究人员的报告相反，本研究中大多数被诊断为物质滥用型精神分裂症的患者已婚。在现有文献中，来自发展中国家的类似研究很少见。
