Farah Roula A, Hage Pierre, Al Rifai Akram, Afif Claude
Department of Pediatrics, St. George Hospital, University of Balamand, Beirut, Lebanon.
J Med Liban. 2010 Oct-Dec;58(4):241-3.
A case of severe thrombocytopenic purpura as the sole manifestation of brucellosis in an eight-year-old boy is presented. Clinical examination revealed mucosal hemorrhages and splenomegaly. The initial diagnosis was immune thrombocytopenic purpura (ITP) and he received intravenous gamma globulins and steroids with good hematologic and clinical response. His brucella agglutination titer was positive and he received treatment with intravenous gentamicin and oral co-trimoxazole with good response. Although mild hematologic manifestations can be encountered in brucellosis, severe thrombocytopenia is rare. Prompt recognition of this association is essential for early therapy. A brief review of thrombo-cytopenic purpura associated with brucellosis is presented.
本文报告了一例8岁男孩以严重血小板减少性紫癜为布鲁氏菌病唯一表现的病例。临床检查发现黏膜出血和脾肿大。初步诊断为免疫性血小板减少性紫癜（ITP），他接受了静脉注射丙种球蛋白和类固醇治疗，血液学和临床反应良好。他的布鲁氏菌凝集试验滴度呈阳性，接受了静脉注射庆大霉素和口服复方新诺明治疗，反应良好。虽然布鲁氏菌病可出现轻度血液学表现，但严重血小板减少罕见。及时识别这种关联对于早期治疗至关重要。本文对与布鲁氏菌病相关的血小板减少性紫癜进行了简要综述。
