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基于纳米粒子的电化学检测在常规和微型系统中的应用及其生物分析应用:综述。

Nanoparticle-based electrochemical detection in conventional and miniaturized systems and their bioanalytical applications: a review.

机构信息

Department of Chemistry, Faculty of Science, Srinakharinwirot University, Sukumvit 23 Rd., Wattana, Bangkok 10110, Thailand.

出版信息

Anal Chim Acta. 2011 Mar 25;690(1):10-25. doi: 10.1016/j.aca.2011.01.054. Epub 2011 Feb 26.

DOI:10.1016/j.aca.2011.01.054
PMID:21414432
Abstract

With recent advances in nanotechnology making more easily available the novel chemical and physical properties of metal nanoparticles (NPs), these have become extremely suitable for creating new sensing assays. Many kinds of NPs, including metal, metal-oxide, semiconductor and even composite-metal NPs, have been used for constructing electrochemical sensors. This article reviews the progress of NP-based electrochemical detection in recent applications, especially in bioanalysis, and summarizes the main functions of NPs in conventional and miniaturized systems. All references cited here generally show one or more of the following characteristics: a low detection limit, good signal amplification and simultaneous-detection capabilities.

摘要

随着纳米技术的最新进展,使得金属纳米粒子(NPs)的新颖化学和物理特性更容易获得,这些特性使得它们非常适合创建新的传感分析。许多类型的 NPs,包括金属、金属氧化物、半导体甚至复合金属 NPs,已被用于构建电化学传感器。本文综述了基于 NPs 的电化学检测在最近的应用中的进展,特别是在生物分析中的应用,并总结了 NPs 在常规和小型化系统中的主要功能。这里引用的所有参考文献通常都具有以下一个或多个特征:低检测限、良好的信号放大和同时检测能力。

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