MRC Epidemiology Lifecourse Unit, Southampton General Hospital, Southampton, Hants SO16 6YD, UK.
Rheumatology (Oxford). 2012 Feb;51(2):230-42. doi: 10.1093/rheumatology/ker086. Epub 2011 Mar 16.
To assess the effectiveness of interventions in community and workplace settings to reduce sickness absence and job loss in workers with musculoskeletal disorders (MSDs).
Relevant randomized controlled trials (RCTs) and cohort studies, published since 1990, were identified by screening citations from 35 earlier systematic reviews and by searching MEDLINE and Embase until April 2010. Effects were estimated by intervention category and other features, including study quality.
Among 42 studies (including 34 RCTs), 27 assessed return to work (RTW), 21 duration of sickness absence and 5 job loss. Interventions included exercise therapy, behavioural change techniques, workplace adaptations and provision of additional services. Studies were typically small {median sample 107 [inter-quartile range (IQR) 77-148]} and limited in quality. Most interventions appeared beneficial: the median relative risk (RR) for RTW was 1.21 (IQR 1.00-1.60) and that for avoiding MSD-related job loss was 1.25 (IQR 1.06-1.71); the median reduction in sickness absence was 1.11 (IQR 0.32-3.20) days/month. However, effects were smaller in larger and better-quality studies, suggesting publication bias. No intervention was clearly superior, although effort-intensive interventions were less effective than simple ones. No cost-benefit analyses established statistically significant net economic benefits.
As benefits are small and of doubtful cost-effectiveness, employers' practice should be guided by their value judgements about the uncertainties. Expensive interventions should be implemented only with rigorous cost-benefit evaluation planned from the outset. Future research should focus on the cost-effectiveness of simple, low-cost interventions, and further explore impacts on job retention.
评估社区和工作场所环境中各种干预措施对减少患有肌肉骨骼疾病(MSD)的劳动者缺勤和失业的效果。
通过筛选 35 项系统综述的参考文献和检索 MEDLINE 和 Embase 数据库(截至 2010 年 4 月),确定了自 1990 年以来发表的相关随机对照试验(RCT)和队列研究。根据干预类别和其他特征(包括研究质量)来评估效果。
在 42 项研究(包括 34 项 RCT)中,有 27 项研究评估了重返工作岗位(RTW),21 项研究评估了缺勤时间,5 项研究评估了失业。干预措施包括运动疗法、行为改变技术、工作场所调整和提供额外服务。研究规模通常较小(中位数样本量为 107[四分位间距(IQR)77-148]),质量有限。大多数干预措施似乎有效:RTW 的中位相对风险(RR)为 1.21(IQR 1.00-1.60),避免 MSD 相关失业的 RR 为 1.25(IQR 1.06-1.71);缺勤减少的中位数为 1.11(IQR 0.32-3.20)天/月。然而,较大和质量较高的研究中效果较小,提示可能存在发表偏倚。没有任何干预措施明显占优势,尽管高强度干预措施不如简单干预措施有效。没有成本效益分析确定了具有统计学意义的净经济效益。
由于效益较小且成本效益不确定,雇主的实践应根据其对不确定性的价值判断来指导。昂贵的干预措施只有在一开始就计划进行严格的成本效益评估的情况下才能实施。未来的研究应侧重于简单、低成本干预措施的成本效益,并进一步探讨其对保留工作岗位的影响。