Vermont Center for Children, Youth, and Families, Department of Psychiatry, University of Vermont, St. Joseph, Room 3213, 1 South Prospect Street, Burlington, VT 05401, USA.
J Am Acad Child Adolesc Psychiatry. 2011 Apr;50(4):364-75. doi: 10.1016/j.jaac.2011.01.004. Epub 2011 Feb 22.
To identify latent classes of posttraumatic stress disorder (PTSD) symptoms in a national sample of adolescents, and to test their associations with PTSD and functional impairment 1 year later.
A total of 1,119 trauma-exposed youth aged 12 through 17 years (mean = 14.99 years, 51% female and 49% male) participating in the National Survey of Adolescents-Replication were included in this study. Telephone interviews were conducted to assess PTSD symptoms and functional impairment at Waves 1 and 2.
Latent Class Analysis revealed three classes of adolescent PTSD at each time point: pervasive disturbance, intermediate disturbance, and no disturbance. Three numbing and two hyperarousal symptoms best distinguished the pervasive and intermediate disturbance classes at Wave 1. Three re-experiencing, one avoidance, and one hyperarousal symptom best distinguished these classes at Wave 2. The Wave 1 intermediate disturbance class was less likely to have a PTSD diagnosis, belong to the Wave 2 pervasive disturbance class, and report functional impairment 1 year later compared with the Wave 1 pervasive disturbance class. The Wave 1 no disturbance class was least likely to have PTSD, belong to the pervasive disturbance class, and report functional impairment at Wave 2.
This study suggests that PTSD severity-distinguishing symptoms change substantially in adolescence and are not characterized by the numbing cluster, contrary to studies in adult samples. These results may help to explain inconsistent factor analytic findings on the structure and diagnosis of PTSD, and emphasize that developmental context is critical to consider in both research and clinical work in PTSD assessment and diagnosis.
在全国青少年样本中确定创伤后应激障碍(PTSD)症状的潜在类别,并检验它们与 PTSD 和 1 年后功能障碍的关联。
共有 1119 名 12 至 17 岁(平均年龄 14.99 岁,51%为女性,49%为男性)的创伤暴露青少年参与了这项全国青少年复制调查,他们被纳入本研究。通过电话访谈在第 1 波和第 2 波评估 PTSD 症状和功能障碍。
潜在类别分析显示,在每个时间点,青少年 PTSD 都有三种类型:普遍困扰、中间困扰和无困扰。在第 1 波,3 个麻木和 2 个过度唤醒症状能最好地区分普遍困扰和中间困扰类。在第 2 波,3 个重新体验、1 个回避和 1 个过度唤醒症状能最好地区分这些类别。与第 1 波普遍困扰类相比,第 1 波中间困扰类更不可能有 PTSD 诊断,更可能属于第 1 波普遍困扰类,且在 1 年后报告功能障碍。第 1 波无困扰类最不可能有 PTSD,最不可能属于普遍困扰类,且在第 2 波报告功能障碍。
这项研究表明,与成人样本中的研究相反,青少年 PTSD 严重程度区分症状发生了很大变化,且不以麻木症状群为特征。这些结果可能有助于解释 PTSD 结构和诊断的不一致的因子分析结果,并强调在 PTSD 评估和诊断的研究和临床工作中,发展背景至关重要。