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中国成年人血脂异常的患病率及相关因素。

Prevalence and associated factors of dyslipidemia in the adult Chinese population.

机构信息

Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

出版信息

PLoS One. 2011 Mar 10;6(3):e17326. doi: 10.1371/journal.pone.0017326.

Abstract

To determine the prevalence, associated factors, awareness and control of dyslipidemia in Chinese living in Greater Beijing, we measured the serum cholesterol concentration in 3251 Chinese adults (age: 45 to 89 years) as participants of the population-based Beijing Eye Study 2006. Additional information on treatment of dyslipidemia was obtained using a standard questionnaire. The mean concentrations of total, HDL cholesterol, LDL cholesterol and triglycerides were 4.92±1.01 mmol/L, 1.61±0.36 mmol/L, 2.88±0.85 mmol/L, and 1.76±1.29 mmol/L, respectively. Prevalence of dyslipidemia was 56.1±0.9%%. Presence of dyslipidemia was significantly associated with increasing age (odds ratio (OR):1.02; 95% confidence interval (CI): 1.01, 1.03), female gender (OR: 1.51; 95%CI: 1.25, 1.83), urban region (OR: 1.82; 95%CI: 1.30, 2.55), body mass index (OR: 1.13; 95%CI: 1.10, 1.15), income (OR: 1.11; 95%CI: 1.02, 1.21), blood glucose concentration (OR: 1.10; 95%CI: 1.05, 1.16), diastolic blood pressure (OR: 1.02; 95%CI: 1.01, 1.03), and smoking (OR: 1.23; 1.01, 1.51). Among those who had dyslipidemia, the proportion of subjects who were aware, treated and controlled was 50.9%, 23.8%, and 39.91%, respectively. The awareness rate was associated with urban region (P = 0.001; OR: 6.50), body mass index (P = 0.001; OR: 1.06), and income (P = 0.02; OR: 1.14). The data suggest that dyslipidemia may be present in about 56% of the population aged 45+ years in Greater Beijing. Factors likely associated with dyslipidemia were higher age, female gender, urban region, higher body mass index, higher income, higher blood concentration of glucose, higher diastolic blood pressure, and smoking. In the examined study population, treatment rate was 24% with about 60% of the treated subjects still having uncontrolled dyslipidemia.

摘要

为了确定居住在北京的中国人血脂异常的流行率、相关因素、知晓率和控制率,我们对作为基于人群的北京眼研究 2006 参与者的 3251 名中国成年人(年龄:45 至 89 岁)进行了血清胆固醇浓度测量。使用标准问卷获得了血脂异常治疗的其他信息。总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和甘油三酯的平均浓度分别为 4.92±1.01mmol/L、1.61±0.36mmol/L、2.88±0.85mmol/L 和 1.76±1.29mmol/L。血脂异常的患病率为 56.1±0.9%。血脂异常的存在与年龄的增加显著相关(比值比(OR):1.02;95%置信区间(CI):1.01,1.03)、女性(OR:1.51;95%CI:1.25,1.83)、城市地区(OR:1.82;95%CI:1.30,2.55)、体重指数(OR:1.13;95%CI:1.10,1.15)、收入(OR:1.11;95%CI:1.02,1.21)、血糖浓度(OR:1.10;95%CI:1.05,1.16)、舒张压(OR:1.02;95%CI:1.01,1.03)和吸烟(OR:1.23;1.01,1.51)。在患有血脂异常的患者中,知晓、治疗和控制的患者比例分别为 50.9%、23.8%和 39.91%。知晓率与城市地区(P=0.001;OR:6.50)、体重指数(P=0.001;OR:1.06)和收入(P=0.02;OR:1.14)有关。这些数据表明,45 岁及以上的北京人中约有 56%可能患有血脂异常。可能与血脂异常相关的因素包括年龄较大、女性、城市地区、较高的体重指数、较高的收入、较高的血糖浓度、较高的舒张压和吸烟。在所检查的研究人群中,治疗率为 24%,而约 60%的治疗患者仍存在未控制的血脂异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/578c/3053360/98c9c7c3eb56/pone.0017326.g001.jpg

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