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北京健康体检人群血脂异常患病率及相关因素

Prevalence of abnormity of blood lipid and associated factors in health examination population in Beijing.

作者信息

Kang Wei-Ming, Zhang Jie-Shi, Liu Xin-Xin, Wang Min-Shan, Zhao Ming-Li, Yu Jian-Chun

机构信息

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

出版信息

Chin Med Sci J. 2009 Sep;24(3):142-6. doi: 10.1016/s1001-9294(09)60078-x.

Abstract

OBJECTIVE

To investigate the prevalence of abnormity of blood lipid and associated factors in healthy population in Beijing.

METHODS

Totally, 38462 individuals who received health examination were enrolled in our study. We divided them into eight groups according to their ages. The levels of serum total cholesterol, triglyceride, high density lipoprotein cholesterol, and low density lipoprotein cholesterol were tested, and the relationship of blood lipid abnormity with body mass index (BMI) and fasting blood glucose was analyzed.

RESULTS

The incidences of hypercholesterolemia, hyperglyceridemia, low high-density lipoprotein cholesterolemia, and hyper low-density lipoprotein cholesterolemia presented increasing trend in this population. The incidence rate of abnormity of blood lipid in health examination population increased with BMI increase. The incidence of abnormity of blood lipid in overweight and obesity population was significantly higher than that in low weight and normal weight populations (P<0.05). Meanwhile, the trend of abnormal blood lipid incidence coincided with that of abnormal fasting blood glucose.

CONCLUSIONS

The prevalence of overweight, obesity, and abnormity of blood lipid in Beijing presents increasing trend. The incidence of abnormity of blood lipid increases with BMI increase, in coincidence with that of fasting blood glucose.

摘要

目的

调查北京市健康人群血脂异常的患病率及相关因素。

方法

本研究共纳入38462名接受健康体检的个体。根据年龄将他们分为八组。检测血清总胆固醇、甘油三酯、高密度脂蛋白胆固醇和低密度脂蛋白胆固醇水平,并分析血脂异常与体重指数(BMI)和空腹血糖的关系。

结果

该人群中高胆固醇血症、高甘油三酯血症、低高密度脂蛋白胆固醇血症和高低密度脂蛋白胆固醇血症的发病率呈上升趋势。健康体检人群血脂异常发病率随BMI升高而增加。超重和肥胖人群血脂异常发病率显著高于低体重和正常体重人群(P<0.05)。同时,血脂异常发病率趋势与空腹血糖异常趋势一致。

结论

北京市超重、肥胖及血脂异常患病率呈上升趋势。血脂异常发病率随BMI升高而增加,与空腹血糖异常情况一致。

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