Iranian Research Center on Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran/Iranian Research Center on Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
PLoS One. 2024 Oct 23;19(10):e0306388. doi: 10.1371/journal.pone.0306388. eCollection 2024.
Dyslipidemia is a major modifiable factor in elderly people. The study objective was to assess the prevalence and associated risk factors of dyslipidemia among the Iranian population aged over 50.
This population-based cross-sectional study is part of the Iranian Longitudinal Study on Ageing conducted in Ardakan, Iran. In total, 5,197 participants aged over 50 years old were included through a stratified random sampling method. Dyslipidemia was defined in compliance with the Adult Treatment Panel III criteria. The Chi-square and independent sample t-test were used to compare categorical and quantitative variables, respectively. A logistic regression analysis was applied to determine associated factors of dyslipidemia.
The mean age of the participants was 62.24±7.52. The prevalence of dyslipidemia was 68.85%. High levels of total cholesterol, triglyceride, low-density lipoprotein, and low level of high-density lipoprotein were seen among 9.74%, 24.66%, 5.54%, 19.20% of the participants, respectively. In addition, 66.05% of the study participants were under the treatment of lipid-lowering medications. Among the possible investigated risk factors of dyslipidemia, male gender (odds ratio (OR) = 0.56, 95% confidence interval (CI): 0.47, 0.68), waist circumference (OR = 1.03, 95%CI: 1.02, 1.04), diabetes mellitus (OR = 2.28, 95%CI: 1.96, 2.66), and hypertension (OR = 1.59, 95%CI: 1.38, 1.83) showed a statistically significant association (p<0.05).
Dyslipidemia is highly prevalent in Ardakan's older population. So, lipid management interventions are necessary for this population.
血脂异常是老年人的一个主要可调节因素。本研究旨在评估伊朗 50 岁以上人群血脂异常的患病率及其相关危险因素。
这是一项基于人群的横断面研究,是伊朗老年纵向研究的一部分,在伊朗阿尔达坎进行。共纳入了 5197 名年龄在 50 岁以上的通过分层随机抽样方法的参与者。血脂异常的定义符合成人治疗小组 III 标准。使用卡方检验和独立样本 t 检验分别比较分类变量和定量变量。应用逻辑回归分析确定血脂异常的相关因素。
参与者的平均年龄为 62.24±7.52 岁。血脂异常的患病率为 68.85%。总胆固醇、甘油三酯、低密度脂蛋白和高密度脂蛋白水平升高的患者比例分别为 9.74%、24.66%、5.54%和 19.20%。此外,66.05%的研究参与者正在服用降脂药物。在血脂异常的可能危险因素中,男性(比值比(OR)=0.56,95%置信区间(CI):0.47,0.68)、腰围(OR=1.03,95%CI:1.02,1.04)、糖尿病(OR=2.28,95%CI:1.96,2.66)和高血压(OR=1.59,95%CI:1.38,1.83)与血脂异常有统计学显著关联(p<0.05)。
阿尔达坎的老年人群中血脂异常的患病率很高。因此,需要对该人群进行血脂管理干预。