Xu G
PUMC Hospital, Beijing.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1990 Apr;12(2):101-4.
Whole blood galactokinase (GK) activities were determined in 278 individuals including 77 patients with senile cataracts, 60 with presenile cataracts and 141 normal controls. No significant difference was found among the GK levels of the three groups. The frequency of GK heterozygocity in the presenile cataract group, however, was significantly higher than that in the normal control group (P less than 0.01), suggesting that even a partial decrease in GK activity might facilitate cataract formation in relatively early stages of life. The intake of milk and its products should be limited, both in GK homo- and heterozygotes.
对278名个体进行了全血半乳糖激酶(GK)活性测定,其中包括77例老年性白内障患者、60例早发性白内障患者和141名正常对照者。三组的GK水平未发现显著差异。然而,早发性白内障组中GK杂合子的频率显著高于正常对照组(P<0.01),这表明即使GK活性有部分降低也可能在生命相对早期阶段促进白内障形成。对于GK纯合子和杂合子,均应限制牛奶及其制品的摄入。