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[Measurement of the erythrocyte galactokinase activity in patients with presenile and senile idiopathic cataract. Preliminary study].

作者信息

Simonelli F, Frunzio S, Rinaldi M, Balestrieri P, Giovane A, Cotticelli L, Rinaldi E

机构信息

Cattedra di Oftalmologia Pediatrica, I Facoltà di Medicina e Chirurgia dell'Università di Napoli.

出版信息

Boll Soc Ital Biol Sper. 1990 Sep;66(9):887-92.

PMID:2073390
Abstract

The activity of galactokinase in red blood cells, has been assayed in 17 patients with idiopathic senile and presenile cataract and in 12 age-matched subjects with perfectly transparent lenses. 3 of the idiopathic cataract patients (17.6%) showed low erythrocytes GK activity, while nobody in the control group showed reduced GK activity. Although preliminary, our results seem to support the possibility that a chronic disorder of galactose metabolism may be involved in the pathogenesis of the idiopathic senile and presenile cataract.

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