海带多糖工业化提取技术及其降血脂功能的研究
[Study on industrialized extraction technology and function of hyperlipidemic regulating of Laminaria japonica polysaccharides].
作者信息
Yuan Ze-Zhi, Cheng Kai-Ming, Huang Wen, Feng Dong-Ru
机构信息
The State Key Laboratory of Biocontrol and The Key Laboratory of Gene Engineering of Ministry of Education, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China.
出版信息
Zhong Yao Cai. 2010 Nov;33(11):1795-8.
OBJECTIVE
To study the industrialized extraction technology and the function of hyperlipidemic regulating of Laminaria japonica polysaccharides.
METHODS
With the orthogonal design L9 (3(4)), different influential elements of the industrialized extraction technology of Laminaria japonica polysaccharides were investigated. Mice treated with different doses of polysaccharides were applied to investigate its-function of hyperlipidemic regulating for 15 days.
RESULTS
5% Na2CO3, 3 hours and 80 degrees C was the best extraction condition, and the extraction rate was 2.13%. Different groups of polysaccharides with different levels of purity and dose lowered the TG, TC level of the mice in various degree.
CONCLUSION
Laminaria japonica polysaccharides have obvious effect on hyperlipidemic regulating.
目的
研究海带多糖的工业化提取工艺及其调节血脂的功能。
方法
采用L9(3(4))正交设计，考察海带多糖工业化提取工艺的不同影响因素。给予不同剂量多糖处理的小鼠15天，以研究其调节血脂的功能。
结果
5%碳酸钠、3小时、80℃为最佳提取条件，提取率为2.13%。不同纯度和剂量水平的多糖组不同程度地降低了小鼠的甘油三酯（TG）、总胆固醇（TC）水平。
结论
海带多糖对调节血脂有明显作用。
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