Aliberti S, Andrisani M C, Tarsia P, Trevisan R, Cosentini R, Longhi L, Pappalettera M, Nosotti M, Blasi F
Dipartimento toraco-polmonare e cardio-circolatorio, University of Milan, IRCCS Fondazione Po.Ma.Re, Milan, Italy.
Monaldi Arch Chest Dis. 2010 Dec;73(4):169-75. doi: 10.4081/monaldi.2010.289.
Patients who undergo lung transplantation are prone to develop lower respiratory tract infections, leading to severe acute respiratory failure (ARF). Endotracheal intubation may not be indicated in these patients in light of a higher rate of mortality due to infections. The application of non-invasive ventilation could play a role in bridging these patients through the episode of ARF waiting for medical treatment to have effect. We report the evidence of morphological and physiological effects of the application of non-invasive continuous positive airway pressure during ARF sustained by pneumonia in a patient who underwent left lung transplantation because of idiopathic pulmonary fibrosis (IPF). We studied the effects of the application of positive end-expiratory pressure on both the right native lung affected by IPF and the transplanted lung affected by pneumonia.
接受肺移植的患者容易发生下呼吸道感染，导致严重的急性呼吸衰竭（ARF）。鉴于感染导致的死亡率较高，这些患者可能不适合进行气管插管。无创通气的应用可能有助于这些患者度过急性呼吸衰竭期，等待治疗起效。我们报告了一名因特发性肺纤维化（IPF）接受左肺移植的患者在肺炎所致急性呼吸衰竭期间应用无创持续气道正压通气的形态学和生理学效应的证据。我们研究了呼气末正压对受IPF影响的右肺和受肺炎影响的移植肺的作用。
