Montasser Dina Ibrahim, Zajjari Yassir, Alayoud Ahmed, Bahadi Abdelali, Aatif Taoufiq, Hassani Kawtar, Hamzi Amine, Allam Mustapha, Benyahia Mohamed, Oualim Zouhir
Service de néphrologie - dialyse et de transplantation rénale, hôpital militaire d'instruction Mohammed V, faculté de médecine et de pharmacie, Hay Riad, CP 10000 Rabat, Maroc.
Nephrol Ther. 2011 Jul;7(4):245-7. doi: 10.1016/j.nephro.2011.02.002. Epub 2011 Mar 23.
The Mediterranean spotted fever is a bacterial infection caused by Rickettsia Conorii mainly around Mediterranean basin. It is often considered like a trivial infection. However, severe forms with a high morbidity and high mortality risk have been described. These forms often associate with impaired consciousness, abnormal liver function, impaired homeostasis, pneumonia and acute renal failure. Several mechanisms of renal damage during the Mediterranean spotted fever have been reported, their pathogenesis remains speculative and the prognosis is determined by the type of renal disease and on early treatment. Thus, rickettsiosis should be considered in combination of acute renal, hepatic cytolysis and thrombocytopenia, allowing rapid achievement of a specific treatment.
地中海斑疹热是一种由康氏立克次体引起的细菌感染，主要发生在地中海盆地周围。它通常被认为是一种轻微感染。然而，已经有严重形式的病例被描述，其发病率和死亡率都很高。这些严重形式常伴有意识障碍、肝功能异常、内环境稳态受损、肺炎和急性肾衰竭。关于地中海斑疹热期间肾脏损伤的几种机制已有报道，但其发病机制仍具有推测性，预后取决于肾脏疾病的类型和早期治疗。因此，当出现急性肾损伤、肝细胞溶解和血小板减少同时存在的情况时，应考虑立克次体病，以便迅速进行特异性治疗。
