Radiology. 2011 Apr;259(1):17-9. doi: 10.1148/radiol.10102253.
Recently, there has been major interest in the identification of biomarkers of early cognitive impairment that may be used to predict subsequent conversion to Alzheimer disease; the data acquired by Chen et al suggest that resting-state functional MR imaging may offer another image-based method to complement promising results arising from quantitative morphometric analysis of anatomic MR images, such as those from recent analyses of the Alzheimer’s Disease Neuroimaging Initiative trial.
最近，人们对识别早期认知障碍的生物标志物产生了浓厚的兴趣，这些标志物可能用于预测随后向阿尔茨海默病的转化；Chen 等人获得的数据表明，静息状态功能磁共振成像可能提供另一种基于图像的方法，以补充解剖磁共振图像定量形态测量分析的有希望的结果，例如最近对阿尔茨海默病神经影像学倡议试验的分析。
