Pannucci Christopher J, Diaz Jose A, Wahl Wendy L
Section of Plastic Surgery, Department of Surgery, University of Michigan, Ann Arbor, Michigan 48105, USA.
J Burn Care Res. 2011 May-Jun;32(3):442-6. doi: 10.1097/BCR.0b013e318217f966.
Previous work has used the National Burn Repository to examine deep venous thrombosis (DVT) after electrical injury. However, these studies were limited and could not examine when DVT occurs after electrical injury. In addition, the utility of risk assessment models for DVT risk stratification has not been examined in this patient population. The authors performed a retrospective chart review of electrically injured patients at a single, American Burn Association- and American College of Surgeons-verified burn center over a 9-year period. Risk factors were identified and used to calculate Caprini scores at baseline and time of discharge. Outcomes of interest included symptomatic DVT or pulmonary embolism and time to DVT or pulmonary embolism. A total of 77 electrically injured patients were identified. DVT incidence was 6.5%. Patients with DVT had significantly higher TBSA (27.8% vs 3.8%), mean number of operations (4.8 vs 0.3), central venous catheter insertion (100% vs 5.3%), ventilator days (16.2 vs 0.3), intensive care unit days (24.4 vs 0.9), and mean change in Caprini score (18.6 vs 1.3) during hospitalization. Baseline Caprini scores were low, and DVT events occurred only after multiple risk factors were present; the average time-to-event was hospital day 17. Among patients with Caprini score >8, DVT incidence increased to 62%. In our single-center experience, the Caprini score was able to quantify DVT risk after electrical injury. In our series of 77 patients, the overall incidence of DVT was 6.5%. However, among patients whose Caprini score reached >8 during hospitalization, DVT incidence increased to 62%.
以往的研究利用国家烧伤资料库来研究电损伤后的深静脉血栓形成(DVT)。然而,这些研究存在局限性,无法探究电损伤后DVT何时发生。此外,尚未在该患者群体中检验DVT风险分层的风险评估模型的效用。作者对一家经美国烧伤协会和美国外科医师学会认证的烧伤中心9年间的电损伤患者进行了回顾性病历审查。确定危险因素并用于计算基线和出院时的Caprini评分。感兴趣的结果包括有症状的DVT或肺栓塞以及发生DVT或肺栓塞的时间。共确定了77例电损伤患者。DVT发生率为6.5%。发生DVT的患者在住院期间的总体表面积(TBSA)显著更高(27.8%对3.8%)、平均手术次数更多(4.8次对0.3次)、中心静脉导管插入率更高(100%对5.3%)、呼吸机使用天数更多(16.2天对0.3天)、重症监护病房天数更多(24.4天对0.9天)以及Caprini评分的平均变化更大(18.6对1.3)。基线Caprini评分较低,且仅在出现多种危险因素后才发生DVT事件;事件发生的平均时间为住院第17天。在Caprini评分>8的患者中,DVT发生率增至62%。根据我们的单中心经验,Caprini评分能够量化电损伤后的DVT风险。在我们的77例患者系列中,DVT的总体发生率为6.5%。然而,在住院期间Caprini评分达到>8的患者中,DVT发生率增至62%。