Werner G S, Corovic D, Buchwald A, Sold G, Kreuzer H, Wiegand V
Abteilung für Kardiologie und Pulmonologie, Zentrum Innere Medizin der Universität Göttingen.
Dtsch Med Wochenschr. 1990 Aug 24;115(34):1259-65. doi: 10.1055/s-2008-1065150.
In 15 patients (13 men, two women, mean age 63 [47-75] years) with peripheral arterial occlusive disease in stages IIB-IV (Fontaine) intravascular ultrasound findings were compared with the angiographic results before and after treatment. In 12 patients stenosis (n = 10) or occlusion (n = 2) of the iliac artery (n = 2) or the superficial femoral artery (n = 10) were treated by conventional balloon angioplasty; in three patients with occlusion of the superficial femoral artery excimer laser angioplasty was performed. There was good correlation between measurements of vessel diameter by the two techniques (r = 0.93, P less than 0.001). Ultrasound scanning provided additional informations regarding the thickness of the plaque, the density or firmness of the stenosis and the degree of calcification. The therapeutic outcome was quantified by measuring the gain in lumen diameter. The authors also assessed the morphological changes following angioplasty in the vicinity of the obstructing plaque. In the light of the ultrasound findings it was considered necessary to undertake further dilatation in four out of the 12 patients treated by balloon dilatation. The results indicate that intravascular ultrasound imaging is a valuable complement to angiography for monitoring of therapeutic results after vascular interventions.
对15例（13例男性，2例女性，平均年龄63[47 - 75]岁）处于IIB - IV期（Fontaine分期）的外周动脉闭塞性疾病患者，比较治疗前后血管内超声检查结果与血管造影结果。12例患者中，髂动脉（2例）或股浅动脉（10例）的狭窄（10例）或闭塞（2例）采用传统球囊血管成形术治疗；3例股浅动脉闭塞患者行准分子激光血管成形术。两种技术测量血管直径之间有良好的相关性（r = 0.93，P＜0.001）。超声扫描提供了关于斑块厚度、狭窄密度或硬度以及钙化程度的额外信息。通过测量管腔直径的增加来量化治疗效果。作者还评估了血管成形术后阻塞斑块附近的形态学变化。根据超声检查结果，12例接受球囊扩张治疗的患者中有4例被认为有必要进一步扩张。结果表明，血管内超声成像对于监测血管介入治疗后的疗效是血管造影的一种有价值的补充。
