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[准分子激光血管成形术治疗动脉阻塞性疾病。导丝控制导管系统的临床经验]

[Excimer laser angioplasty in arterial obstructive disease. Clinical experience with guidewire-controlled catheter systems].

作者信息

Werner G S, Buchwald A, von Romatowski J, Unterberg C, Sauthoff G, Wurm K, Kreuzer H, Wiegand V

机构信息

Abteilung für Kardiologie und Pulmonologie, Universität Göttingen.

出版信息

Dtsch Med Wochenschr. 1989 Aug 25;114(34):1271-5. doi: 10.1055/s-2008-1066752.

DOI:10.1055/s-2008-1066752
PMID:2527736
Abstract

Percutaneous transluminal laser angioplasties (PTLA) were performed in nine patients (7 males, 2 females, aged 52-81 years) with peripheral vascular disease, stages IIB-IV (Fontaine's classification), with 75% stenosis (5 patients) or occlusion (4 patients) in the area of the superficial femoral artery. Two catheter systems were used. One was a monofiber catheter (600 microns) with eccentric guidewire, the other a multifiber catheter with 12 concentrically arranged fibres (200 microns each) and a central guidewire. An XeCl-excimer laser (308 nm), with a pulse duration of 50 ns and pulse frequency of 15-30 Hz, served as the laser source. It was possible in all patients to reduce the stenosis of 75-100% to 35-70% or reopen the occlusion without laser-associated complications. To remove the residual stenosis PTLA was followed by balloon dilatation in seven patients and by application of a Simpson atherectomy catheter in one patient: these measures reduced the degree of stenosis to 20-40%.

摘要

对9例(7例男性,2例女性,年龄52 - 81岁)患有外周血管疾病、处于IIB - IV期(Fontaine分类法)的患者进行了经皮腔内激光血管成形术(PTLA),这些患者的股浅动脉区域存在75%的狭窄(5例)或闭塞(4例)。使用了两种导管系统。一种是带有偏心导丝的单纤维导管(600微米),另一种是带有12根同心排列纤维(每根200微米)和中心导丝的多纤维导管。一台XeCl准分子激光器(308纳米),脉冲持续时间为50纳秒,脉冲频率为15 - 30赫兹,用作激光源。所有患者都有可能将75% - 100%的狭窄程度降低到35% - 70%,或重新开通闭塞处,且未出现与激光相关的并发症。为消除残余狭窄,7例患者在PTLA后进行了球囊扩张,1例患者应用了Simpson旋切导管:这些措施将狭窄程度降低到了20% - 40%。

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