Laboratoire de Biochimie et de Technobiologie, Faculté des Sciences de Tunis, Campus Universitaire, 2092 El-Manar II, Tunisia.
Eur J Clin Microbiol Infect Dis. 2011 Oct;30(10):1267-70. doi: 10.1007/s10096-011-1222-1. Epub 2011 Mar 27.
A collection of 20 multidrug-resistant Providencia stuartii isolates recovered from 2005 to 2009 at the Military Hospital of Tunis, Tunisia, was analysed. They all expressed the extended-spectrum β-lactamase (ESBL) VEB-1a. The bla (VEB-1a) gene was plasmid-located and it was associated with complex genetic structures, including Re elements. Pulsed-field gel electrophoresis (PFGE) revealed a clonal relationship between all of these isolates. This study identified a nosocomial dissemination of an ESBL-producing P. stuartii clone in a Tunisian hospital over a long period of time.
对 2005 年至 2009 年从突尼斯突尼斯军事医院收集的 20 株多药耐药普罗威登斯菌的分离株进行了分析。它们都表达了扩展谱β-内酰胺酶（ESBL）VEB-1a。bla（VEB-1a）基因位于质粒上，与包括 Re 元件在内的复杂遗传结构相关。脉冲场凝胶电泳（PFGE）显示所有这些分离株之间存在克隆关系。本研究在突尼斯一家医院发现了一种产 ESBL 的铜绿假单胞菌克隆在很长一段时间内在医院内的传播。
