Esser G, Laucht M, Schmidt M, Löffler W, Reiser A, Stöhr R M, Weindrich D, Weinel H
Zentralinstitut für Seelische Gesundheit, Kinder- und Jugendpsychiatrische Klinik, Mannheim, Federal Republic of Germany.
Eur Arch Psychiatry Neurol Sci. 1990;239(6):384-90. doi: 10.1007/BF01734547.
In a prospective longitudinal study starting at birth 384 infants and their families were investigated. The subjects were distributed across the nine cells of a two-factorial design (3 x 3), factor 1 representing the degree of organic, factor 2 the degree of psychosocial risk. At age 3 months there was a significant influence of organic risk factors on all developmental parameters. Psychosocial risks were only relevant for cognitive development and behaviour problems. Organic high-risk children who adapted quickly after birth showed an especially good development status.
在一项从出生开始的前瞻性纵向研究中，对384名婴儿及其家庭进行了调查。受试者分布在两因素设计（3×3）的九个单元格中，因素1代表器质性程度，因素2代表心理社会风险程度。在3个月大时，器质性风险因素对所有发育参数都有显著影响。心理社会风险仅与认知发展和行为问题相关。出生后适应迅速的器质性高危儿童表现出特别良好的发育状况。
