Hadders-Algra M, Huisjes H J, Touwen B C
Department of Developmental Neurology, University Hospital, Groningen, The Netherlands.
Dev Med Child Neurol. 1988 Aug;30(4):482-91. doi: 10.1111/j.1469-8749.1988.tb04775.x.
A prospective study was carried out on 133 neurologically deviant infants, 205 with mild abnormalities and 230 normal newborns to compare behavioural and cognitive development with neonatal and nine-year-old neurological condition. Overtly handicapped children were excluded. Major determinants of school failure were the severity of minor neurological dysfunction (MND) and social class. Main risk factors for distractable and clumsy behaviour were MND classification and male sex; for troublesome behaviour male sex and interval complications after two years of age; and for timid behaviour, family adversity. Definite neonatal neurological deviancy contributed both directly and by its association with MND to problems in behaviour and scholastic abilities. Mild neonatal neurological abnormalities and adverse obstetrical events contributed only indirectly to behavioural and learning problems. Preterm birth (less than 34 weeks) was the sole obstetric variable directly related to some of the outcome variables. The difference between home and school perception of the children's behaviour is emphasized.
对133名神经发育异常的婴儿、205名有轻度异常的婴儿和230名正常新生儿进行了一项前瞻性研究,以比较其行为和认知发展与新生儿期及9岁时神经状况的关系。明显有残疾的儿童被排除在外。学业失败的主要决定因素是轻度神经功能障碍(MND)的严重程度和社会阶层。注意力分散和行为笨拙的主要危险因素是MND分类和男性性别;麻烦行为的主要危险因素是男性性别和两岁后出现的间歇性并发症;而胆小行为的主要危险因素是家庭逆境。明确的新生儿神经发育异常直接以及通过与MND的关联导致行为和学业能力方面的问题。轻度新生儿神经异常和不良产科事件仅间接导致行为和学习问题。早产(少于34周)是唯一与某些结果变量直接相关的产科变量。强调了家庭和学校对儿童行为认知的差异。