Miettunen Jouko, Veijola Juha, Isohanni Matti, Paunio Tiina, Freimer Nelson, Jääskeläinen Erika, Taanila Anja, Ekelund Jesper, Järvelin Marjo-Riitta, Peltonen Leena, Joukamaa Matti, Lichtermann Dirk
Department of Psychiatry, Oulu University and Oulu University Hospital, Oulu, Finland.
J Nerv Ment Dis. 2011 Apr;199(4):230-8. doi: 10.1097/NMD.0b013e3182125d2c.
We study the predictive power and associations of several psychopathology and temperament scales with respect to schizophrenia and other psychotic disorders. Measures of psychopathology (Physical and Social Anhedonia Scales, Perceptual Aberration Scale, Hypomanic Personality Scale, Bipolar II Scale, and Schizoidia Scale) and the Temperament and Character Inventory were included in the 31-year follow-up of the prospective Northern Finland 1966 birth cohort (N = 4926). The Perceptual Aberration Scale was the best scale for concurrent validity in psychoses, and also the best psychopathology scale in terms of discriminant validity. Participants scoring high in hypomanic personality were at the highest risk for developing psychosis during the 11-year follow-up. Harm avoidance was a dominant temperament dimension in individuals with psychosis compared with participants without psychiatric diagnoses. These scales are useful as vulnerability markers in studying psychoses.
我们研究了几种精神病理学和气质量表对精神分裂症及其他精神障碍的预测能力和相关性。在对芬兰北部1966年出生队列（N = 4926）进行的31年随访中，纳入了精神病理学测量指标（身体和社交快感缺失量表、感知偏差量表、轻躁狂人格量表、双相II型量表和类精神分裂症量表）以及气质与性格量表。感知偏差量表在精神病的同时效度方面是最佳量表，在判别效度方面也是最佳的精神病理学量表。在11年的随访期间，轻躁狂人格得分高的参与者患精神病的风险最高。与未被诊断为精神疾病的参与者相比，回避伤害是患有精神病的个体中占主导地位的气质维度。这些量表在研究精神病时作为易感性标志物很有用。
