Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun 130022, Jilin, China.
Chem Commun (Camb). 2011 May 14;47(18):5289-91. doi: 10.1039/c1cc10953g. Epub 2011 Mar 31.
We present a PdCl(2)-catalyzed protocol for highly efficient allylation and benzylation of a rich variety of N-, O-, and S-containing heteroarenes under base/acid, additive, and ligand-free conditions. The method represents the very few examples for simple, universally applicable, clean, and atom-efficient functionalization of heteroarenes.
我们提出了一个 PdCl(2) 催化的协议，用于在碱/酸、添加剂和配体自由条件下高效地对各种 N-、O-和 S-含杂环芳烃进行烯丙基化和苄基化。该方法代表了少数几个简单、通用、清洁和原子经济性的杂环芳烃官能化的例子。
