Katipoğlu Zeynep, Zengin Nazmi
Ophthalmology Department, Polatlı Duatepe State Hospital, Ankara 06900, Turkey.
Ophthalmology Department, Necmettin Erbakan University, Konya, Turkey.
Ther Adv Ophthalmol. 2021 Jun 30;13:25158414211027757. doi: 10.1177/25158414211027757. eCollection 2021 Jan-Dec.
This study aimed to determine the relationship between clinical symptoms and findings of patients diagnosed with conjunctivochalasis in our clinic and the risk factors reported in the literature, to determine new possible etiological factors, and to compare routine tear assessment methods with novel strip meniscometry in these patients.
The study included patients who presented to our clinic between March 2019 and June 2019 and were diagnosed with conjunctivochalasis. The Ocular Surface Disease Index was used to assess ocular surface symptoms. Anterior segment examination included tear break-up time, corneal staining, localization of conjunctivochalasis, and the presence of pinguecula or pterygium. For each patient, tears were measured using both Schirmer and strip meniscometry. Patients with conjunctivochalasis were evaluated as lid-parallel conjunctival folds grade 1, 2, or 3.
There was a total of 57 participants, including 31 women (54.4%) and 26 men (45.6%). Lid-parallel conjunctival folds grade was found to be statistically significantly associated with dust exposure ( = 0.034). Multiple regression analysis revealed that dust exposure was an independent predictor of being diagnosed with lid-parallel conjunctival folds grade 2 lid-parallel conjunctival folds grade 1 (odds ratio = 3.515, = 0.029). Moreover, Schirmer's test and strip meniscometry results were positively correlated in patients with conjunctivochalasis ( = 0.302 and = 0.022).
We conclude that external factors are prominent in patients with conjunctivochalasis, especially dust exposure. In addition, strip meniscometry may be preferred as a more practical and noninvasive alternative to investigate dry eye symptoms in patients with conjunctivochalasis.
本研究旨在确定在我们诊所被诊断为结膜松弛症的患者的临床症状和检查结果与文献中报道的危险因素之间的关系，确定新的可能病因，并比较这些患者常规泪液评估方法与新型泪河测量法。
该研究纳入了2019年3月至2019年6月期间到我们诊所就诊并被诊断为结膜松弛症的患者。使用眼表疾病指数评估眼表症状。眼前节检查包括泪膜破裂时间、角膜染色、结膜松弛症的定位以及睑裂斑或翼状胬肉的存在情况。对每位患者使用泪液试纸试验和新型泪河测量法测量泪液。将结膜松弛症患者评估为睑结膜平行皱襞1级、2级或3级。
共有57名参与者，包括31名女性（54.4%）和26名男性（45.6%）。发现睑结膜平行皱襞分级与接触灰尘在统计学上显著相关（P = 0.034）。多元回归分析显示，接触灰尘是被诊断为睑结膜平行皱襞2级而非1级的独立预测因素（比值比 = 3.515，P = 0.029）。此外，在结膜松弛症患者中，泪液试纸试验和新型泪河测量法的结果呈正相关（P = 0.302，P = 0.022）。
我们得出结论，外部因素在结膜松弛症患者中较为突出，尤其是接触灰尘。此外，新型泪河测量法作为一种更实用且无创的方法，可能更适合用于调查结膜松弛症患者的干眼症状。
